Recombinant Human EPHB6 EPHB6-28625TH

Recombinant Human EPHB6

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Recombinant Human EPHB6

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Cat.No. : EPHB6-28625TH
Product Overview : Recombinant fragment of Human Eph receptor B6 with N-terminal proprietary tag. Predicted MW 36.63 kDa.
Description : Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ephrin receptor encoded by this gene lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands.
Protein length : 100 amino acids
Molecular Weight : 36.630kDa inclusive of tags
Source : Wheat germ
Tissue specificity : Expressed in brain. Expressed in non invasive breast carcinoma cell lines (at protein level). Strong expression in brain and pancreas, and weak expression in other tissues, such as heart, placenta, lung, liver, skeletal muscle and kidney. Expressed in bre
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : DTTGETSEIGWLTYP PGGWDEVSVLDDQRR LTRTFEACHVAGAPP GTGQDNWLQTHFVER RGAQRAHIRLHFSVR ACSSLGVSGGTCRET FTLYYRQAEE
Sequence Similarities : Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.Contains 2 fibronectin type-III domains.Contains 1 protein kinase domain.Contains 1 SAM (sterile alpha motif) domain.
Gene Name : EPHB6 EPH receptor B6 [ Homo sapiens ]
Official Symbol : EPHB6
Synonyms : EPHB6; EPH receptor B6; EphB6; ephrin type-B receptor 6; HEP;
Gene ID : 2051
mRNA Refseq : NM_004445
Protein Refseq : NP_004436
MIM : 602757
Uniprot ID : O15197
Chromosome Location : 7q33-q35
Pathway : Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem;
Function : ATP binding; ephrin receptor activity; nucleotide binding; protein kinase activity; receptor activity;

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