Recombinant Human EXOSC10, His-tagged EXOSC10-26640TH

Recombinant Human EXOSC10, His-tagged

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Recombinant Human EXOSC10, His-tagged

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Cat.No. : EXOSC10-26640TH
Product Overview : Recombinant full length EXOSC10 protein produced from Sf9 insect cells. This is a glycosylated, polypeptide chain with a MW of 120 kDa,with a N termial 6xHis tag.
Description : Exosome component 10, also known as EXOSC10, is a human gene, the protein product of which is part of the exosome complex and is an autoantigen is patients with certain auto immune diseases, most notably scleromyositis.
Conjugation : HIS
Biological activity : This protein binds IgG-type human auto-antibodies and polymyositis patient sera.
Form : Liquid
Storage buffer : Preservative: NoneConstituents: 0.02% SDS, 20mM HEPES, 100mM Sodium chloride, 0.01mM EDTA, pH 7.5
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequence Similarities : Contains 1 3-5 exonuclease domain.Contains 1 HRDC domain.
Gene Name : EXOSC10 exosome component 10 [ Homo sapiens ]
Official Symbol : EXOSC10
Synonyms : EXOSC10; exosome component 10; PMSCL2, polymyositis/scleroderma autoantigen 2, 100kDa; p2; p3; p4; PM Scl; PM/Scl 100; polymyositis/scleroderma autoantigen 2 (100kD); RRP6; Rrp6p;
Gene ID : 5394
mRNA Refseq : NM_001001998
Protein Refseq : NP_001001998
MIM : 605960
Uniprot ID : Q01780
Chromosome Location : 1p36.22
Pathway : RNA degradation, organism-specific biosystem; RNA degradation, conserved biosystem;
Function : 3-5 exonuclease activity; RNA binding; exoribonuclease activity; hydrolase activity; nucleotide binding;

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