Recombinant Human EXOSC10 Protein, GST-tagged

• Cat.No.: EXOSC10-3567H
• Product Overview: Human EXOSC10 full-length ORF ( NP_001001998.1, 1 a.a. - 885 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: EXOSC10 (Exosome Component 10) is a Protein Coding gene. Diseases associated with EXOSC10 include Systemic Scleroderma and Collagen Disease. Among its related pathways are rRNA processing in the nucleus and cytosol and Deadenylation-dependent mRNA decay. GO annotations related to this gene include nucleic acid binding and nucleotide binding.
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 127.2 kDa
• AA Sequence: MAPPSTREPRVLSATSATKSDGEMV LPGFPDADSFVKFALGSVVAVTKAS GGLPQFGDEYDFYRSFPGFQAFCET QGDRLLQCMSRVMQYHGCRSNIKDR SKVTELEDKFDLLVDANDVILERVG ILLDEASGVNKNQQPVLPAGLQVPK TVVSSWNRKAAEYGKKAKSETFRLL HAKNIIRPQLKFREKIDNSNTPFLP KIFIKPNAQKPLPQALSKERRERPQ DRPEDLDVPPALADFIHQQRTQQVE QDMFAHPYQYELNHFTPADAVLQKP QPQLYRPIEETPCHFISSLDELVEL NEKLLNCQEFAVDLEHHSYRSFLGL TCLMQISTRTEDFIIDTLELRSDMY ILNESLTDPAIVKVFHGADSDIEWL QKDFGLYVVNMFDTHQAARLLNLGR HSLDHLLKLYCNVDSNKQYQLADWR IRPLPEEMLSYARDDTHYLLYIYDK MRLEMWERGNGQPVQLQVVWQRSRD ICLKKFIKPIFTDESYLELYRKQKK HLNTQQLTAFQLLFAWRDKTARRED ESYGYVLPNHMMLKIAEELPKEPQG IIACCNPVPPLVRQQINEMHLLIQQ AREMPLLKSEVAAGVKKSGPLPSAE RLENVLFGPHDCSHAPPDGYPIIPT SGSVPVQKQASLFPDEKEDNLLGTT CLIATAVITLFNEPSAEDSKKGPLT VAQKKAQNIMESFENPFRMFLPSLG HRAPVSQAAKFDPSTKIYEISNRWK LAQVQVQKDSKEAVKKKAAEQTAAR EQAKEACKAAAEQAISVRQQVVLEN AAKKRERATSDPRTTEQKQEKKRLK ISKKPKDPEPPEKEFTPYDYSQSDF KAFAGNSKSKVSSQFDPNKQTPSGK KCIAAKKIKQSVGNKSMSFPTGKSD RGFRYNWPQR
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: EXOSC10 exosome component 10 [ Homo sapiens ]
• Official Symbol: EXOSC10
• Synonyms: EXOSC10; exosome component 10; PMSCL2, polymyositis/scleroderma autoantigen 2, 100kDa; p2; p3; p4; PM Scl; PM/Scl 100; polymyositis/scleroderma autoantigen 2 (100kD); RRP6; Rrp6p; autoantigen PM-SCL; autoantigen PM/Scl 2; polymyositis/scleroderma autoantigen 100 kDa; polymyositis/scleroderma autoantigen 2, 100kDa; P100 polymyositis-scleroderma overlap syndrome-associated autoantigen; PMSCL; PM-Scl; PMSCL2; PM/Scl-100
• Gene ID: 5394
• mRNA Refseq: NM_001001998
• Protein Refseq: NP_001001998
• MIM: 605960
• UniProt ID: Q01780