Recombinant Human GGT1

• Cat.No.: GGT1-29019TH
• Product Overview: Recombinant full length Human GGT1 with N terminal proprietary tag; Predicted MWt 88.40 kDa inclusive of tag.

Specification

• Description: The enzyme encoded by this gene catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein, and is present in tissues involved in absorption and secretion. This enzyme is a member of the gamma-glutamyltransferase protein family, of which many members have not yet been fully characterized and some of which may represent pseudogenes. This gene is classified as type I gamma-glutamyltransferase. Multiple alternatively spliced variants, encoding the same protein, have been identified.
• Protein length: 569 amino acids
• Molecular Weight: 88.400kDa inclusive of tags
• Source: Wheat germ
• Tissue specificity: Detected in fetal and adult kidney and liver, adult pancreas, stomach, intestine, placenta and lung. Isoform 3 is lung-specific. There are several other tissue-specific forms that arise from alternative promoter usage but that produce the same protein.
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the gamma-glutamyltransferase family.

Gene Information

• Gene Name: GGT1 gamma-glutamyltransferase 1 [ Homo sapiens ]
• Official Symbol: GGT1
• Synonyms: GGT1; gamma-glutamyltransferase 1; GGT; gamma-glutamyltranspeptidase 1; CD224; D22S672; D22S732
• Gene ID: 2678
• mRNA Refseq: NM_001032364
• Protein Refseq: NP_001027536
• MIM: 612346
• Uniprot ID: P19440
• Chromosome Location: 22q11.23
• Pathway: Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Biological oxidations, organism-specific biosystem; Cyanoamino acid metabolism, organism-specific biosystem; Cyanoamino acid metabolism, conserved biosystem
• Function: gamma-glutamyltransferase activity; gamma-glutamyltransferase activity; protein binding; transferase activity, transferring acyl groups