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Recombinant Human GGT1

Cat.No.: GGT1-29019TH
Product Overview: Recombinant full length Human GGT1 with N terminal proprietary tag; Predicted MWt 88.40 kDa inclusive of tag.
Description: The enzyme encoded by this gene catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein, and is present in tissues involved in absorption and secretion. This enzyme is a member of the gamma-glutamyltransferase protein family, of which many members have not yet been fully characterized and some of which may represent pseudogenes. This gene is classified as type I gamma-glutamyltransferase. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Protein length: 569 amino acids
Molecular Weight: 88.400kDa inclusive of tags
Source: Wheat germ
Tissue specificity: Detected in fetal and adult kidney and liver, adult pancreas, stomach, intestine, placenta and lung. Isoform 3 is lung-specific. There are several other tissue-specific forms that arise from alternative promoter usage but that produce the same protein.
Form: Liquid
Purity: Proprietary Purification
Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities: Belongs to the gamma-glutamyltransferase family.
Gene Name: GGT1 gamma-glutamyltransferase 1 [ Homo sapiens ]
Official Symbol: GGT1
Synonyms: GGT1; gamma-glutamyltransferase 1; GGT; gamma-glutamyltranspeptidase 1; CD224; D22S672; D22S732;
Gene ID: 2678
mRNA Refseq: NM_001032364
Protein Refseq: NP_001027536
MIM: 612346
Uniprot ID: P19440
Chromosome Location: 22q11.23
Pathway: Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Biological oxidations, organism-specific biosystem; Cyanoamino acid metabolism, organism-specific biosystem; Cyanoamino acid metabolism, conserved biosystem;
Function: gamma-glutamyltransferase activity; gamma-glutamyltransferase activity; protein binding; transferase activity, transferring acyl groups;

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