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Recombinant Human MAX, FLAG-tagged

Cat.No.: MAX-28524TH
Product Overview: Recombinant full length Human MAX with Flag tag; amino acids 1-160 , 19 kDa.
Description: The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature for some of them is unknown.
Conjugation: FLAG
Source: E. coli
Form: Liquid
Purity: Immunogen affinity purified
Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 20mM Tris Cl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Gene Name: MAX MYC associated factor X [ Homo sapiens ]
Official Symbol: MAX
Synonyms: MAX; MYC associated factor X; MAX protein; protein max; bHLHd4; bHLHd5; bHLHd6; bHLHd7; bHLHd8;
Gene ID: 4149
mRNA Refseq: NM_002382
Protein Refseq: NP_002373
MIM: 154950
Uniprot ID: P61244
Chromosome Location: 14q23
Pathway: C-MYC pathway, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Cyclin A:Cdk2-associated events at S phase entry, organism-specific biosystem; Cyclin E associated events during G1/S transition, organism-specific biosystem; G1/S Transition, organism-specific biosystem;
Function: protein binding; protein complex binding; protein heterodimerization activity; protein homodimerization activity; sequence-specific DNA binding;

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