||RecombinantHuman PDK2 amino acids 16 - 407 with N-terminal His tag.
||This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
||392 amino acids
||Expressed in many tissues, with the highest level in heart and skeletal muscle, intermediate levels in brain, kidney, pancreas and liver, and low levels in placenta and lung.
||pH: 7.50Constituents:0.08% DTT, 0.14% Sodium phosphate, 1.46% Sodium chloride, 30% Glycerol, 0.015% EDTA, 0.05% Triton-X-100
||Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
||Belongs to the PDK/BCKDK protein kinase family.Contains 1 histidine kinase domain.