Recombinant Human PDK2, His-tagged
Cat.No. : | PDK2-29162TH |
Product Overview : | RecombinantHuman PDK2 amino acids 16 - 407 with N-terminal His tag. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Protein length : | 392 amino acids |
Conjugation : | HIS |
Tissue specificity : | Expressed in many tissues, with the highest level in heart and skeletal muscle, intermediate levels in brain, kidney, pancreas and liver, and low levels in placenta and lung. |
Form : | Liquid |
Storage buffer : | pH: 7.50Constituents:0.08% DTT, 0.14% Sodium phosphate, 1.46% Sodium chloride, 30% Glycerol, 0.015% EDTA, 0.05% Triton-X-100 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the PDK/BCKDK protein kinase family.Contains 1 histidine kinase domain. |
Gene Name : | PDK2 pyruvate dehydrogenase kinase, isozyme 2 [ Homo sapiens ] |
Official Symbol : | PDK2 |
Synonyms : | PDK2; pyruvate dehydrogenase kinase, isozyme 2; pyruvate dehydrogenase kinase, isoenzyme 2; PDHK2; |
Gene ID : | 5164 |
mRNA Refseq : | NM_001199898 |
Protein Refseq : | NP_001186827 |
MIM : | 602525 |
Uniprot ID : | Q15119 |
Chromosome Location : | 17q21.33 |
Pathway : | B Cell Receptor Signaling Pathway, organism-specific biosystem; Metabolism, organism-specific biosystem; Pyruvate metabolism, organism-specific biosystem; Pyruvate metabolism and Citric Acid (TCA) cycle, organism-specific biosystem; Regulation of pyruvate dehydrogenase (PDH) complex, organism-specific biosystem; |
Function : | ATP binding; nucleotide binding; protein kinase activity; pyruvate dehydrogenase (acetyl-transferring) kinase activity; transferase activity; |
Products Types
◆ Recombinant Protein | ||
Pdk2-4767M | Recombinant Mouse Pdk2 Protein, Myc/DDK-tagged | +Inquiry |
PDK2-1639H | Recombinant Human PDK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
PDK2-4009R | Recombinant Rat PDK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
PDK2-6608M | Recombinant Mouse PDK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Pdk2-8052M | Recombinant Mouse Pdk2 protein, His & T7-tagged | +Inquiry |
◆ Lysates | ||
PDK2-3329HCL | Recombinant Human PDK2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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