||Full length Human Plasminogen mature protein purified from human plasma.
||The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.
||Present in plasma and many other extracellular fluids. It is synthesized in the liver.
||Activity: >120 units per mg protein.One unit is defined as the amount of enzyme, which will hydrolyze 1 micromole of N-tosyl-L-arginine ester in 30 minutes at 37°C at pH 8.0.
||Lyophilised:Reconstitute with 467ul distilled water.
||>95% by SDS-PAGE
||Preservative: NoneConstituents: 20mM Tris, 2mM EDTA, pH 7.5
||Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
||Belongs to the peptidase S1 family. Plasminogen subfamily.Contains 5 kringle domains.Contains 1 PAN domain.Contains 1 peptidase S1 domain.