"DNMT1" Related Products

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Recombinant Human DNMT1, GST-tagged

Cat. No. : DNMT1-511H
Product Overview : Recombinant Human DNMT1, (a-a 2-1632), with N-terminal GST tag expressed inbaculovirus. MW= 211 kDa.
Description : DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities.
Source : Baculovirus.
Purity : >50%.
Application : Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Formulated In : 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20 and 10% glycerol.
Stability : >6 months at –80°C.
Gene Name : DNMT1 DNA (cytosine-5-)-methyltransferase 1 [ Homo sapiens ]
Synonyms : DNMT1; DNA (cytosine-5-)-methyltransferase 1; AIM; DNMT; MCMT; CXXC9; FLJ16293; MGC104992; CXXC finger protein 9; DNA methyltransferase 1; EC 2.1.1.37; Dnmt1; DNA methyltransferase HsaI; DNA MTase HsaI; M.HsaI; CXXC-type zinc finger protein 9
Gene ID : 1786
mRNA Refseq : NM_001130823
Protein Refseq : NP_001124295
MIM : 126375
UniProt ID : P26358
Chromosome Location : 19p13.2
Pathway : Cysteine and methionine metabolism; Metabolic pathways
Function : DNA (cytosine-5-)-methyltransferase activity; DNA binding; metal ion binding; transcription factor binding; transferase activity; zinc ion binding

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