|Product Overview :
||Recombinant fragment, corresponding to amino acids 1-299 of Human RIP2, was expressed by baculovirus in Sf9 insect cells using a N-terminal tag, MW 59 kDa.
||This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.
|Tissue specificity :
||Detected in heart, brain, placenta, lung, peripheral blood leukocytes, spleen, kidney, testis, prostate, pancreas and lymph node.
|Storage buffer :
||Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
||Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
|Sequence Similarities :
||Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.Contains 1 CARD domain.Contains 1 protein kinase domain.