Recombinant Human SELL, Fc-tagged
Cat.No. : | SELL-27885TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 1-343 of Human CD62L fused to the Fc region of human IgG1 , expressed in modified human 293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. |
Conjugation : | Fc |
Tissue specificity : | Expressed in B cell lines and T lymphocytes. |
Form : | Lyophilised:It is recommended that 0.5 ml of sterile phosphate-buffered saline be added to the vial.Following reconstitution short-term storage at 4°C is recommended, and longer-term storage of aliquots at -18 to -20°C. Repeated freeze thawing is not reco |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 10% Trehalose, 1% Human serum albumin, PBS |
Storage : | Store at +4°C. |
Sequences of amino acids : | Theoretical Sequence:WTYHYSEKPMNWQRARRFCRDNYTDLVAI QNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVGTNK SLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDD ACHKLKAALCYTASCQPWSCSGHGECVEIINNYTCNCD VGYYGPQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSS QCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEP LSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKK KTICESSGIWSNPSPICQKLDKSFSMIKEGDWIPKVDK KVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMI SRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKP REEQYNSTYRVVSVLTVLHQDWLNGKEYKCRVSNKALP APIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLV KGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLY SKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSP GK |
Sequence Similarities : | Belongs to the selectin/LECAM family.Contains 1 C-type lectin domain.Contains 1 EGF-like domain.Contains 2 Sushi (CCP/SCR) domains. |
Gene Name : | SELL selectin L [ Homo sapiens ] |
Official Symbol : | SELL |
Synonyms : | SELL; selectin L; LNHR, LYAM1, lymphocyte adhesion molecule 1; L-selectin; CD62L; hLHRc; LAM 1; LAM1; Leu 8; LSEL; Lyam 1; PLNHR; |
Gene ID : | 6402 |
mRNA Refseq : | NM_000655 |
Protein Refseq : | NP_000646 |
MIM : | 153240 |
Uniprot ID : | P14151 |
Chromosome Location : | 1q23-q25 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Hemostasis, organism-specific biosystem; |
Function : | carbohydrate binding; cell adhesion molecule binding; glycosphingolipid binding; heparin binding; protease binding; |
Products Types
◆ Recombinant Protein | ||
Sell-165M | Recombinant Mouse Sell Protein, His (Fc)-Avi-tagged | +Inquiry |
SELL-227H | Recombinant Human SELL Protein, His-tagged | +Inquiry |
Sell-5756M | Recombinant Mouse Sell Protein, His-tagged | +Inquiry |
SELL-3949R | Recombinant Rhesus Macaque SELL Protein, His (Fc)-Avi-tagged | +Inquiry |
SELL-233H | Recombinant Human SELL Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
SELL-2614MCL | Recombinant Mouse SELL cell lysate | +Inquiry |
SELL-1963HCL | Recombinant Human SELL cell lysate | +Inquiry |
SELL-1131CCL | Recombinant Cynomolgus SELL cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket