Native Human SERPINF2


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Native Human SERPINF2

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Cat.No. : SERPINF2-27292TH
Product Overview : Full length native Alpha 2 Antiplasmin purified from human plasma, 70kDa.
Description : This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.
Biological activity : Specific activity:13.05 IU/mgSERPINF2-27292TH efficiently inhibits the plasminogen-activator-induced lysis of fibrin clots.
Form : Lyophilised:Reconstitution is batch dependent. We deliver 100ug lyophilised product. Please add the correct volume of distilled water to achieve the lot specific concentration indicated on the vial.
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 200mM Sodium chloride, 20mM Bis-Tris, pH 6.4
Storage : Store at -20°C. Stable for 12 months at -20°C
Gene Name : SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 [ Homo sapiens ]
Official Symbol : SERPINF2
Synonyms : SERPINF2; serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2; PLI, serine (or cysteine) proteinase inhibitor, clade F (alpha 2 antiplasmin, pigment epithelium derived factor), member 2; alpha-2-antiplas
Gene ID : 5345
mRNA Refseq : NM_000934
Protein Refseq : NP_000925
MIM : 613168
Uniprot ID : P08697
Chromosome Location : 17pter-p12
Pathway : Blood Clotting Cascade, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Dissolution of Fibrin Clot, organism-specific biosystem;
Function : endopeptidase inhibitor activity; protease binding; protein binding; serine-type endopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity;

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