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Recombinant Mouse Selectin, Lymphocyte, Fc-His

Cat.No. : Sell-1764M
Product Overview : The extracellular doman of mouse L-selectin was fused to the carboxy-terminal 6X his-tagged Fc region of human IgG1 via a polypeptide linker inserted into a suitable mammalian expression vector and expressed inNS0 cells.
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Cat. No. : Sell-1764M
Description : L-selectin, also known as CD62L, is a cell adhesion molecule consisting of a large, highly glycosylated, extracellular domain found on leukocytes. It belongs to the selectin family of proteins, which recognise sialylated carbohydrate groups. L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via the high endothelial venules. L-selectin is an effective marker for separating lymphoid progenitors from myeloid progenitors and hematopoietic stem cells in bone marrow.
Molecular Weight : The predicted molecular weight of Recombinant Mouse L-Selectin is Mr 60.5 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 150 kDa.
Source : Mammalian cells
State Of Matter : Lyophilized.
Purity : >90% by SDS Page and analyzed by silver stain.
Formulation : This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.
Endotoxin : <0.1 EU/µg as determined by the LAL method.
Biological Activity : The biological activity of Mouse L-Selectin was determined by the ability of the immobilized protein to support the adhesion of LS180 cells. When 1 x 104cells/well are added to L-Selectin coated plates approximately 90 - 100% will adhere for 1 hour incubation at RT.
Storage And Stability : This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Gene Name : Sell selectin, lymphocyte [ Mus musculus ]
Synonyms : Sell; selectin, lymphocyte; Lnhr; CD62L; Ly-22; Lyam1; Ly-m22; Lyam-1; LECAM-1; AI528707; L-selectin; selectin L
Gene ID : 20343
mRNA Refseq : NM_001164059
Protein Refseq : NP_001157531
UniProt ID : P18337
Chromosome Location : 86.6 cM
Pathway : Cell adhesion molecules (CAMs)
Function : Binding; protein binding; sugar binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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