Recombinant Human Acyl-Coenzyme A dehydrogenase, His tagged ACADS-1829H

Recombinant Human Acyl-Coenzyme A dehydrogenase, His tagged

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Recombinant Human Acyl-Coenzyme A dehydrogenase, His tagged

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Cat. No. : ACADS-1829H
Product Overview : Recombinant human ACADS protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques.
Description : ACADS (Acyl-Coenzyme A dehydrogenase), also known as SCAD or ACAD3, is a tetrameric mitochondrial flavoprotein, which is a member of the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutations of ACADS have been associated with fatty acid oxidation defects and metabolic diseases such as short-chain acyl-CoA dehydrogenase deficiency (SCAD deficiency).
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MLHTIYQSVE LPETHQMLLQ TCRDFAEKEL FPIAAQVDKE HLFPAAQVKK MGGLGLLAMD VPEELGGAGL DYLAYAIAME EISRGCASTG VIMSVNNSLY LGPILKFGSK EQKQAWVTPF TSGDKIGCFA LSEPGNGSDA GAASTTARAE GDSWVLNGTK AWITNAWEAS AAVVFASTDR ALQNKSISAF LVPMPTPGLT LGKKEDKLGI RGSSTANLIF EDCRIPKDSI LGEPGMGFKI AMQTLDMGRI GIASQALGIA QTALDCAVNY AENRMAFGAP LTKLQVIQFK LADMALALES ARLLTWRAAM LKDNKKPFIK EAAMAKLAAS EAATAISHQA IQILGGMGYV TEMPAERHYR DARITEIYEG TSEIQRLVIA GHLLRSYRS
Form : Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT 0.1 M Nacl, and 20% glycerol
Molecular Weight : 44.0 kDa (409aa)
Purity : > 95% by SDS - PAGE
Concentration : 0.5 mg/ml (determined by Bradford assay)
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways : Butanoate metabolism; Fatty acid metabolism; Metabolic pathways; Valine, leucine and isoleucine degradation; Metabolism of lipids and lipoproteins.
Gene Name : ACADS acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain [ Homo sapiens ]
Synonyms : ACADS; SCAD; ACAD3; acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain; short-chain acyl-CoA dehydrogenase; butyryl-CoA dehydrogenase; unsaturated acyl-CoA reductase; short chain acyl-CoA dehydrogenase; EC 1.3.99.2; Butyryl-CoA dehydrogenase
Gene ID : 35
mRNA Refseq : NM_000017
Protein Refseq : NP_000008
MIM : 606885
UniProt ID : P16219
Chromosome Location : 12q22-qter
Function : FAD binding; acyl-CoA binding; butyryl-CoA dehydrogenase activity.

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