Recombinant Human Delta-like 1 Homolog (Drosophila), FLAG-tagged
Cat.No. : | DLK1-2079H |
Product Overview : | Recombinant HumanDLK1 is produced inHEK 293 Cells. Signal peptide and extracellular domain of human Dlk1 (aa 1-303) are fused at the C-terminus to a FLAG-tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | DLK1-2079H |
Description : | This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass. |
Source : | HEK 293 Cells. |
Concentration : | ~1mg/ml. |
Formulation : | Liquid. 0.2µm-filtered solution in PBS. |
Endotoxin Content : | <0.1EU/µg protein (LAL-test). |
Purity : | ≥90% (SDS-PAGE). |
Storage : | Working aliquots are stable for up to 3 months when stored at -20°C. |
Handling : | After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. |
Gene Name : | DLK1 delta-like 1 homolog (Drosophila) [ Homo sapiens ] |
Synonyms : | DLK1; delta-like 1 homolog (Drosophila); DLK; FA1; ZOG; pG2; PREF1; Pref-1; protein delta homolog 1; DLK-1; secredeltin; fetal antigen 1; preadipocyte factor 1 |
Gene ID : | 8788 |
mRNA Refseq : | NM_003836 |
Protein Refseq : | NP_003827 |
MIM : | 176290 |
UniProt ID : | P80370 |
Chromosome Location : | 14q32 |
Function : | molecular_function; protein binding |
Products Types
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Dlk1-2400M | Recombinant Mouse Dlk1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
DLK1-6909HCL | Recombinant Human DLK1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionDLK1 has been found to play a role in cellular senescence, and understanding this process may have implications for aging-related research.
Yes, there are clinical trials exploring the therapeutic potential of targeting DLK1 in cancer treatment and regenerative medicine.
DLK1 is involved in the regulation of adipocyte differentiation, and understanding its role may have implications for obesity-related research.
DLK1 is involved in the regulation of stem cell differentiation, making it a potential target for therapeutic applications in regenerative medicine.
Modulating DLK1 expression holds promise for therapeutic interventions, such as controlling cell growth in cancer or enhancing tissue regeneration.
Customer Reviews (3)
Write a reviewIn addition to these experimental benefits, the manufacturer of DLK1 protein plays a vital role in supporting researchers.
DLK1 protein demonstrates exceptional stability and consistency, ensuring reliable and reproducible results throughout the duration of the trial.
DLK1 protein exhibits high bioactivity, enabling efficient and effective interactions with its molecular targets.
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