Active Recombinant Mouse Acvr2b protein, His-tagged
Cat.No. : | Acvr2b-424M |
Product Overview : | Recombinant Mouse Acvr2b protein(NP_031423.1)(Met1-Thr134), fused with His tag, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Mouse |
Tag : | His |
Form : | Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA. |
Bio-activity : | 1. Measured by its binding ability in a functional ELISA. Immobilized Mouse ACVR2B at 2μg/mL (100 μl/well) can bind biotinylated mouse INHBA-His, The EC50 of biotinylated mouse INHBA-His is 40-95 ng/mL.2. Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 0.2-0.8 µg/mL in the presence of 10 ng/mL recombinant Activin A. |
Molecular Mass : | The recombinant mouse ACTRIIB/ACVR2B comprises 127 amino acids and has a predicted molecular mass of 14.8 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmACVR2B is approximately 33-37 kDa due to glycosylation. |
Proteinlength : | Met1-Thr134 |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 94 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | Acvr2b activin receptor IIB [ Mus musculus ] |
Official Symbol : | Acvr2b |
Synonyms : | ACVR2B; activin receptor IIB; activin receptor type-2B; ACTR-IIB; activin receptor type IIB; ActRIIB; |
Gene ID : | 11481 |
mRNA Refseq : | NM_007397 |
Protein Refseq : | NP_031423 |
Products Types
◆ Recombinant Protein | ||
Acvr2b-529M | Recombinant Mouse Acvr2b Protein, MYC/DDK-tagged | +Inquiry |
ACVR2B-011M | Active Recombinant Mouse ACVR2B Protein, Fc-tagged | +Inquiry |
ACVR2B-151R | Recombinant Rat ACVR2B Protein, His (Fc)-Avi-tagged | +Inquiry |
ACVR2B-02H | Recombinant Active Human ACVR2B Protein, GST-tagged | +Inquiry |
ACVR2B-275H | Recombinant Human ACVR2B Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ACVR2B-2540MCL | Recombinant Mouse ACVR2B cell lysate | +Inquiry |
ACVR2B-2724HCL | Recombinant Human ACVR2B cell lysate | +Inquiry |
ACVR2B-734CCL | Recombinant Cynomolgus ACVR2B cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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