"PDP2" Related Products

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Recombinant Human PDP2, His-tagged

Cat. No.: PDP2-699H
Product Overview: Recombinant Human PDP2 with a His tag is expressed inBacteriaand column-purified.
Description: PDH kinases (PDK"s) deactivate PDH by reversible phosphorylation. In humans and rodents, 4 PDK"s are present in an organ-dependent manner. In all cases, PDK"s are physically part of the PDH complex (binding via lipoyl domain 2 of E2), and they phosphorylate the E1 subunit at 3 specific serine residues. PDH phosphatases remove the phosphorylation and restore activity of PDH.
Source: Bacteria.
Storage: Store at -80°C.
Gene Name: PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 [ Homo sapiens ]
Synonyms: PDP2; pyruvate dehyrogenase phosphatase catalytic subunit 2; PDP 2; PDPC 2; [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial; protein phosphatase 2C, magnesium-dependent, catalytic subunit 2; pyruvate dehydrogenase phosphatase catalytic subunit 2; pyruvate dehydrogenase phosphatase isoenzyme 2; pyruvate dehydrogenase phosphatase, catalytic subunit 2; PPM2C2; KIAA1348
Gene ID: 57546
mRNA Refseq: NM_020786
Protein Refseq: NP_065837
UniProt ID: Q9P2J9
Chromosome Location: 16q22.1
Pathway: Integration of energy metabolism; Pyruvate metabolism and Citric Acid (TCA) cycle
Function: [pyruvate dehydrogenase (lipoamide)] phosphatase activity; calcium ion binding; hydrolase activity; magnesium-dependent protein serine/threonine phosphatase activity; protein complex binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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