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Active Recombinant Human PLK1 protein, His-tagged

Cat.No. : PLK1-785H
Product Overview : Recombinant Human PLK1 protein(NP_005021.2)(Met1-Ser603), fused with His tag, was expressed in Insect Cells.
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Source : Insect Cells
Species : Human
Tag : His
Form : Supplied as sterile 50mM Tris, 100mM NaCl, pH 7.4, 0.5mM EDTA, 0.5mM EGTA, 0.5mM PMSF, 25% glycerolPlease contact us for any concerns or special requirements.Please refer to the specific buffer information in the hard copy of CoA.
Bio-activity : The specific activity was determined to be >3 nmol/min/mg using casein as substrate.
Molecular Mass : The recombinant human PLK1 consists of 621 amino acids and predicts a molecular mass of 70.5 kDa. It migrates as an approximately 66 kDa band in SDS-PAGE under reducing conditions.
Protein Length : Met1-Ser603
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 90 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : PLK1 polo-like kinase 1 [ Homo sapiens ]
Official Symbol : PLK1
Synonyms : PLK1; polo-like kinase 1; PLK, polo like kinase (Drosophila); serine/threonine-protein kinase PLK1; PLK-1; polo like kinase; polo (Drosophia)-like kinase; serine/threonine-protein kinase 13; cell cycle regulated protein kinase; PLK; STPK13;
Gene ID : 5347
mRNA Refseq : NM_005030
Protein Refseq : NP_005021
MIM : 602098
UniProt ID : P53350

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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How can PLK1 inhibitors be used in combination with other cancer treatments? 03/16/2023

PLK1 inhibitors can be combined with chemotherapy or radiation therapy to enhance their effectiveness in treating certain types of cancer.

What are the potential clinical applications of PLK1 inhibitors in cancer treatment? 11/24/2019

PLK1 inhibitors are being investigated as potential cancer therapies to target and inhibit the overactive PLK1 in cancer cells.

Are there any specific cancer types where PLK1 inhibitors have shown promise in clinical trials? 08/01/2019

PLK1 inhibitors have shown promise in clinical trials for various cancer types, including breast, lung, and colorectal cancers.

How do researchers target PLK1 specifically in cancer cells without affecting healthy cells? 03/19/2019

This is a significant challenge, and researchers are working on developing selective inhibitors that primarily target cancer cells.

Can PLK1 protein be used as a biomarker for cancer diagnosis? 05/10/2016

PLK1 levels can be elevated in some cancers, and its expression can be used as a diagnostic or prognostic biomarker.

Customer Reviews (3)

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09/14/2022

    the manufacturer's dedication to continuous improvement and innovation is evident in their ongoing efforts to enhance the PLK1 protein's performance and optimize its applications.

    02/26/2017

      The exceptional quality and reliability of the PLK1 protein provided by the manufacturer cannot be overstated.

      03/09/2016

        Its purity and consistency guarantee accurate and consistent results, allowing for confident data interpretation and analysis.

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