Human TDO Fluorogenic Inhibitor Screening Assay Kit
Cat.No. : | Kit-1761 |
Product Overview : | L-tryptophan (L-Trp) is an essential amino acid necessary for protein synthesis in mammalian cells and the L-Trp to kynurenine (Kyn) pathway is firmly established as a key regulator of innate and adaptive immunity. Catabolism of L-Trp to Kyn maintains an immunosuppressive microenvironment by starving immune cells of L-Trp and releasing degradation products of L-Trp that have immunosuppressive functions., Tryptophan 2,3 dioxygenase (TDO) a rate limiting enzymes in this pathway, is upregulated in many tumors, providing cancer cells with an avenue for immune evasion. |
- Specification
- Gene Information
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Size : | 96 reactions |
Applications : | Useful for the study of TDO enzymology, inhibitor screening, and selectivity profiling. |
Storage : | Stable at least 6 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival. |
Products Types
◆ Recombinant Protein | ||
TDO-85A | Active Recombinant Anopheles gambiae TDO, His-tagged | +Inquiry |
◆ Assay kits | ||
Kit-1762 | Human TDO Inhibitor Screening Assay Kit (384) | +Inquiry |
Kit-1760 | Human TDO Cell-Based Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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