Mouse IDO2 Inhibitor Screening Assay Kit
Cat.No. : | Kit-1783 |
Product Overview : | L-tryptophan (L-Trp) is an essential amino acid necessary for protein synthesis in mammalian cells and the L-Trp to kynurenine (Kyn) pathway is firmly established as a key regulator of innate and adaptive immunity. Catabolism of L-Trp to Kyn maintains an immunosuppressive microenvironment by starving immune cells of L-Trp and releasing degradation products of L-Trp that have immunosuppressive functions. Indoleamine 2,3- dioxygenases (IDO1 & IDO2), two of the rate limiting enzymes in this pathway, are upregulated in many tumors, providing cancer cells with an avenue for immune evasion. |
- Specification
- Gene Information
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Size : | 96 reactions |
Applications : | Useful for the study of mouse IDO2 enzymology, screening inhibitors, and selectivity profiling. |
Storage : | At least 6 months from date of receipt when stored as directed. |
Products Types
◆ Recombinant Protein | ||
IDO2-1139H | Recombinant Human IDO2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ido2-3475M | Recombinant Mouse Ido2 Protein, Myc/DDK-tagged | +Inquiry |
Ido2-1645R | Recombinant Rat Ido2 Protein, His-tagged | +Inquiry |
IDO2-1420H | Recombinant Human IDO2 Protein (14-420 aa), His-tagged | +Inquiry |
Ido2-1176M | Recombinant Mouse Ido2 protein, His-tagged | +Inquiry |
◆ Lysates | ||
IDO2-5299HCL | Recombinant Human IDO2 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1759 | Human IDO2 Inhibitor Screening Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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