PARPtrap Assay Kit
| Cat.No. : | Kit-1805 |
| Product Overview : | PARP1 is known to bind damaged DNA through its N-terminal zinc finger domain. After PARP1 ribosylates itself (autoribosylation), it dissociates from DNA due to the accumulated negative charge of the ribosyl polymer. Trapped PARP-DNA complexes have been shown to be cytotoxic to cancer cells. |
- Specification
- Gene Information
- Related Products
| Size : | 96 reactions |
| Applications : | Great for screening small molecules that enhance PARP1/DNA trapping for drug discovery and HTS applications. |
| Storage : | Up to 1 year when stored as recommended. |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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