Recombinant Bovine Fibroblast Growth Factor 2
| Cat.No. : | FGF2-650B |
| Product Overview : | Recombinantbovine FGF2 is a single, non-glycosylated polypeptide chain containing 172amino acids. |
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| Cat. No. : | FGF2-650B |
| Description : | FGF2 is a single-chainpolypeptide growth factor that plays a significant role in the process ofwound healing and is a potent inducer of angiogenesis. Several different formsof the human protein exist ranging from 18-24 kDa in size due to the use of alternativestart sites within the FGF2 gene. |
| Source : | Bovine |
| Host : | E. coli |
| Form : | Lyophilized from asterile filtered solution in PBS, pH 7.4 + 4% mannitol. |
| Purity : | >97% by SDS-PAGEand HPLC analyses. |
| Sequence : | MTMITNSSSVPGDPLESMAA GSITTLPALP EDGGSGAFPP GHFKDPKRLY CKNGGFFLRI HPDGRVDGVR EKSDPHIKLQLQAEERGVVS IKGVCANRYL AMKEDGRLLA SKCVTDECFF FERLESNNYN TYRSRKYSSW YVALKRTGQY KLGPKTGPGQKAILFLPMSA KS |
| Molecular Weight : | 18.5 kDa |
| Biological Activity : | Calculated by the dose dependantproliferation of BALB/c 3T3 cells, the ED50 is < 1.0 ng/ml. |
| Endotoxin : | <1 ng/μg of FGF2 |
| Reconstitution : | Centrifugevial prior to opening. Add sterile distilled water or aqueousbuffer to a concentration of 0.1-1.0 mg/ml. Further dilutions should be madein appropriate buffered solutions. |
| Storage : | Stable at2-8°C, but best kept desiccated -20°C. Upon reconstitution, stable for up to1 week at 2-8°C. For longer term, store in working aliquots below -20°C.Avoid repeated freeze/thaw cycles. |
| OfficialSymbol : | FGF2 |
| Pathways : | MAPKsignaling pathway; Melanoma; Pathways in cancer; Regulation of actincytoskeleton |
| Tag : | Non |
| Gene Name : | FGF2 fibroblastgrowth factor 2 (basic) [ Bos taurus ] |
| Synonyms : | FGF2; fibroblast growthfactor 2 (basic); heparin-binding growth factor 2; BFGF; HBGF-2;basic fibroblast growth factor; Heparin-binding growth factor 2; Basicfibroblast growth factor; bFGF; FGF-2 |
| Gene ID : | 281161 |
| mRNA Refseq : | NM_174056 |
| Protein Refseq : | NP_776481 |
| UniProt ID : | P03969 |
| Chromosome Location : | 17 |
| Function : | growth factor activity; heparinbinding; protein binding; voltage-gated calcium channel activity |
Products Types
| ◆ Recombinant Protein | ||
| FGF2-15H | Active Recombinant Human FGF2 Protein, Pre-aliquoted | +Inquiry |
| FGF2-78P | Recombinant Active Pig FGF2 Protein, His-tagged(N-ter) | +Inquiry |
| FGF2-039H | Recombinant Human FGF2 Protein | +Inquiry |
| FGF2-401F | Active Recombinant Human FGF2 Protein (146 aa) | +Inquiry |
| FGF2-6755R | Recombinant Rabbit FGF2 protein, His-SUMO-tagged | +Inquiry |
| ◆ Native Protein | ||
| FGF2-26551TH | Native Human FGF2 | +Inquiry |
| FGF2-34B | Active Native Bovine bFGF | +Inquiry |
| ◆ Lysates | ||
| FGF2-638HCL | Recombinant Human FGF2 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (2)
Write a reviewThe technical expert communicated with me in time to understand the progress of my experiment and gave me suggestions for improvement.
The purchased protein is suitable for WB experiments and I am satisfied with the results.
Q&As (6)
Ask a questionFGF2 promotes cell migration and angiogenesis and regulates bone homeostatic balance.
FGF2 is widely expressed in the nervous system.
FGF2 is mainly expressed in tissues such as mammary glands and ovaries of sheep.
FGF1 has a high degree of homology with FGF2.
FGF2 is involved in diseases such as cardiovascular disease, breast disease and bone homeostasis.
FGF2 negatively regulates bone homeostasis.
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