Recombinant Clostridium Botulinum BOTF Protein (1-436 aa), His-tagged
| Cat.No. : | BOTF-1599C |
| Product Overview : | Recombinant Clostridium Botulinum BOTF Protein (1-436 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Protein Description: Partial. |
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| Description : | Botulinum toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '58-Gln-|-Lys-59' bond of synaptobrevins-1 and -2. |
| Source : | Yeast |
| Species : | Clostridium Botulinum |
| Tag : | His |
| Form : | Tris-based buffer,50% glycerol |
| Molecular Mass : | 51.6 kDa |
| Protein length : | 1-436 aa |
| AA Sequence : | MPVAINSFNYNDPVNDDTILYMQIP YEEKSKKYYKAFEIMRNVWIIPERN TIGTNPSDFDPPASLKNGSSAYYDP NYLTTDAEKDRYLKTTIKLFKRINS NPAGKVLLQEISYAKPYLGNDHTPI DEFSPVTRTTSVNIKLSTNVESSML LNLLVLGAGPDIFESCCYPVRKLID PDVVYDPSNYGFGSINIVTFSPEYE YTFNDISGGHNSSTESFIADPAISL AHELIHALHGLYGARGVTYEETIEV KQAPLMIAEKPIRLEEFLTFGGQDL NIITSAMKEKIYNNLLANYEKIATR LSEVNSAPPEYDINEYKDYFQWKYG LDKNADGSYTVNENKFNEIYKKLYS FTESDLANKFKVKCRNTYFIKYEFL KVPNLLDDDIYTVSEGFNIGNLAVN NRGQSIKLNPKIIDSIPDKGLVEKI VKFCKSVIPRK |
| Purity : | > 90% as determined by SDS-PAGE. |
| Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
| Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
| Concentration : | A hardcopy of COA with reconstitution instruction is sent along with the products. |
| Synonyms : | botF; Bontoxilysin-F; |
| UniProt ID : | P30996 |
| Synonyms : | botF; Bontoxilysin-F; |
| UniProt ID : | P30996 |
Products Types
| ◆ Recombinant Protein | ||
| BOTF-927C | Recombinant Clostridium Botulinum BOTF Protein (1-436 aa), His-tagged | +Inquiry |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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