| Description : |
The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. |
| Source : |
HEK293 |
| Species : |
Cynomolgus monkey |
| Tag : |
Fc |
| Form : |
Lyophilized |
| Molecular Mass : |
45.8 kDa |
| Protein Length : |
302 |
| AA Sequence : |
MFSHLPFDCVLLLLLLLLTRSSEVE YIAEVGQNAYLPCSYTPAPPGNLVP VCWGKGACPVFDCSNVVLRTDNRDV NDRTSGRYWLKGDFHKGDVSLTIEN VTLADSGVYCCRIQIPGIMNDEKHN VKLVVIKPAKVTPAPTLQRDLTSAF PRMLTTGEHGPAETQTPGSLPDVNL TVSNFFCELQIFTLTNELRDSGATI RTAIYIAAGISAGLALALIFGALIF KWYSHSKEKTQNLSLISLANIPPSG LANAVAEGIRSEENIYTIEEDVYEV EEPNEYYCYVSSGQQPSQPLGCRVA MP |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
