Recombinant Escherichia coli RDGB Protein (1-197 aa), His-SUMO-Myc-tagged
| Cat.No. : | RDGB-2500E |
| Product Overview : | Recombinant Escherichia coli (strain K12) RDGB Protein (1-197 aa) is produced by E. coli expression system. This protein is fused with a 10xHis-SUMO tag at the N-terminal and a Myc tag at the C-terminal. Protein Description: Full Length. |
- Specification
- Gene Information
- Related Products
| Description : | Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Can also efficiently hydrolyze 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP). Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.To a much lesser extent,is also able to hydrolyze GTP, dGTP and dUTP, but shows very low activity toward the canonical nucleotides dATP, dCTP and dTTP and toward 8-oxo-dGTP, purine deoxyribose triphosphate, 2-aminopurine deoxyribose triphosphate and 2,6-diaminopurine deoxyribose triphosphate. |
| Source : | E. coli |
| Species : | E. coli |
| Tag : | His-SUMO-Myc |
| Form : | Tris-based buffer,50% glycerol |
| Molecular Mass : | 41.0 kDa |
| Protein length : | 1-197 aa |
| AA Sequence : | MQKVVLATGNVGKVRELASLLSDFG LDIVAQTDLGVDSAEETGLTFIENA ILKARHAAKVTALPAIADDSGLAVD VLGGAPGIYSARYSGEDATDQKNLQ KLLETMKDVPDDQRQARFHCVLVYL RHAEDPTPLVCHGSWPGVITREPAG TGGFGYDPIFFVPSEGKTAAELTRE EKSAISHRGQALKLLLDALRNG |
| Purity : | > 85% as determined by SDS-PAGE. |
| Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
| Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
| Concentration : | A hardcopy of COA will be sent along with the products. Please refer to it for detailed information. |
| Gene Name : | rdgB dITP/XTP pyrophosphatase [ Escherichia coli str. K-12 substr. MG1655 ] |
| Official Symbol : | RDGB |
| Synonyms : | rdgB; ECK2949; yggV; |
| Gene ID : | 947429 |
| Protein Refseq : | NP_417429 |
| UniProt ID : | P52061 |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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