| Description : |
The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). Finally, this gene is found on chromosome 20, immediately downstream of the BPI gene. |
| Source : |
In Vitro Cell Free System |
| Species : |
Human |
| Form : |
Liquid |
| Molecular Mass : |
75.830kDa inclusive of tags |
| Protein Length : |
452 amino acids |
| AA Sequence : |
ANPGLVARITDKGLQYAAQEGLLALQSELLRITLPDFTGD LRIPHVGRGRYEFHSLNIHSCELLHSALRPVPGQGLSLSI SDSSIRVQGRWKVRKSFFKLQGSFDVSVKGISISVDLLLG SESSGRPTVTASSCSSDIADVEVDMSGDLGWLLNLFHNQI ESKFQKVLESRICEMIQKSVSSDLQPYLQTLPVTTEIDSF ADIDYSLVEAPRATAQMLEVMFKGEIFHRNHRSPVTLLAA VMSLPEEHNKMVYFAISDYVFNTASLVYHEEGYLNFSITD DMIPPDSNIRLTTKSFRPFVPRLARLYPNMNLELQGSVPS APLLNFSPGNLSVDPYMEIDAFVLLPSSSKEPVFRLSVAT NVSATLTFNTSKITGFLKPGKVKVELKESKVGLFNAELLE ALLNYYILNTFYPKFNDKLAEGFPLPLLKRVQLYDLGLQI HKDFPSRRDHPP |
| Purity : |
Proprietary Purification |
| Storage : |
Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles. |
| Storage Buffer : |
pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione. |
