Recombinant Mouse LBP Protein
Cat.No. : | LBP-8975M |
Product Overview : | Recombinant Mouse LBP full length or partial length protein was expressed. |
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Source : | Mammalian Cells |
Species : | Mouse |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC. |
Storage Buffer : | PBS buffer |
Gene Name : | Lbp lipopolysaccharide binding protein [ Mus musculus ] |
Official Symbol : | LBP |
Gene ID : | 16803 |
mRNA Refseq : | NM_008489.2 |
Protein Refseq : | NP_032515.2 |
MIM : | |
UniProt ID : | Q61805 |
Products Types
◆ Recombinant Protein | ||
LBP-3338H | Recombinant Human LBP Protein, His (Fc)-Avi-tagged | +Inquiry |
Lbp-5007M | Recombinant Mouse Lbp Protein, His (Fc)-Avi-tagged | +Inquiry |
LBP-5008M | Recombinant Mouse LBP Protein, His (Fc)-Avi-tagged | +Inquiry |
LBP-3339H | Recombinant Human LBP Protein, His (Fc)-Avi-tagged | +Inquiry |
LBP-007H | Recombinant Human LBP Protein, His-tagged | +Inquiry |
◆ Lysates | ||
LBP-1853HCL | Recombinant Human LBP cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionIf LPS's chemical spatial configuration prevents close contact with TLR4, it exhibits an antagonistic effect, inhibiting the cellular response.
LPS on the LBP-LPS complex, upon close physical contact with TLR4 on cells, induces TLR4 receptor dimerization or multimerization. This activates various transcription factors, leading to the expression of inflammatory mediators and cytokines.
For cells without membrane CD14 receptors (e.g., endothelial and epithelial cells), a soluble CD14 (sCD14)-LBP-LPS ternary complex forms, activating TLR4 and inducing various biological effects.
LBP stands for Lipopolysaccharide-Binding Protein.
LBP has a high affinity for the lipid A portion in the structure of Lipopolysaccharide (LPS) and forms the LPS-LBP complex.
Liver cells, similar to macrophages, express mCD14 and TLR4. In the absence of CD14 receptors, LPS can still bind to TLR4, but with relatively weaker intensity.
The LBP-LPS complex can transfer LPS to membrane CD14 (mCD14) receptors on cells like monocytes, macrophages, and neutrophils.
Customer Reviews (3)
Write a reviewWe appreciated the product's efforts to minimize its environmental footprint through sustainable manufacturing practices.
Its adaptability to various sample types and conditions made it a valuable asset for our diverse projects.
The product's versatility allowed us to apply it to a wide range of experimental techniques and research areas.
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