| Description : |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in several protein-coding and non-protein-coding variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
68.6 kDa |
| AA Sequence : |
MAVAGPAPGAGARPRLDLQFLQRFL QILKVLFPSWSSQNALMFLTLLCLT LLEQFVIYQVGLIPSQYYGVLGNKD LEGFKTLTFLAVMLIVLNSTLKSFD QFTCNLLYVSWRKDLTEHLHRLYFR GRAYYTLNVLRDDIDNPDQRISQDV ERFCRQLSSMASKLIISPFTLVYYT YQCFQSTGWLGPVSIFGYFILGTVV NKTLMGPIVMKLVHQEKLEGDFRFK HMQIRVNAEPAAFYRAGHVEHMRTD RRLQRLLQTQRELMSKELWLYIGIN TFDYLGSILSYVVIAIPIFSGVYGD LSPTELSTLVSKNAFVCIYLISCFT QLIDLSTTLSDVAGYTHRIGQLRET LLDMSLKSQDCEILGESKWGLDTPP GWPAAEPADTAFLLERVSISAPSSD KPLIKDLSLKISEGQSLLITGNTGT GKTSLLRVLGGLWTSTRGSVQMLTD FGPHGVLFLPQKPFFTDGTLREQVI YPLKEVYPDSGSADDERILRFLELA GLSNLVARTEGLDQQVDWNWYDVLS PGEMQRLSFARLFYLQPKYAVLDEA TSALTEEVESELYRIGQQLGMTFIS VGHRQSLEKFHSLVLKLCGGGRWEL MRIKVETRTRPLEQKLISEEDLAAN DILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
