Recombinant Mouse Abcd4 Protein, Myc/DDK-tagged

• Cat.No.: Abcd4-1461M
• Product Overview: Purified recombinant protein of mouse full-length ATP-binding cassette, sub-family D (ALD), member 4 (cDNA clone MGC:60642 IMAGE:30012556), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that the human protein may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis.
• Molecular Mass: 58.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Abcd4 ATP-binding cassette, sub-family D (ALD), member 4 [ Mus musculus (house mouse) ]
• Official Symbol: Abcd4
• Synonyms: Abcd4; ATP-binding cassette, sub-family D (ALD), member 4; P6; Pxm; P69r; P70R; Pxmp1l; lysosomal cobalamin transporter ABCD4; ATP-binding cassette sub-family D member 4; PMP69; PMP70-related protein; PXMP1-L; peroxisomal membrane protein 69; peroxisomal membrane protein, 70 kDa-related
• Gene ID: 19300
• mRNA Refseq: NM_008992
• Protein Refseq: NP_033018
• UniProt ID: O89016