Recombinant Human ALAS1 Protein, His-tagged

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Recombinant Human ALAS1 Protein, His-tagged

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Cat.No. : ALAS1-312H
Product Overview : Recombinant Human ALAS1, transcript variant 2, fused with His tag at N-terminal was expressed in E. coli.
Description : THis gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by tHis gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of tHis gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms.
Source : E. coli
Tag : His
Form : 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl. Store at -80 centigradeentigradeentigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Molecular Mass : 70.4 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : ALAS1 aminolevulinate, delta-, synthase 1 [ Homo sapiens ]
Official Symbol : ALAS1
Synonyms : ALAS1; aminolevulinate, delta-, synthase 1; ALAS, ALAS3; 5-aminolevulinate synthase, nonspecific, mitochondrial; ALAS-H; delta-ALA synthase 1; migration-inducing protein 4; 5-aminolevulinic acid synthase 1; delta-aminolevulinate synthase 1; ALAS; MIG4; ALAS3; ALASH;
Gene ID : 211
mRNA Refseq : NM_000688
Protein Refseq : NP_000679
MIM : 125290
UniProt ID : P13196
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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