Recombinant Human ALDH7A1 Protein, GST-tagged

• Cat.No.: ALDH7A1-452H
• Product Overview: Human ALDH7A1 full-length ORF ( NP_001173.1, 1 a.a. - 511 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified. [provided by RefSeq, Jan 2011]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 81.8 kDa
• AA Sequence: MSTLLINQPQYAWLKELGLREENEG VYNGSWGGRGEVITTYCPANNEPIA RVRQASVADYEETVKKAREAWKIWA DIPAPKRGEIVRQIGDALREKIQVL GSLVSLEMGKILVEGVGEVQEYVDI CDYAVGLSRMIGGPILPSERSGHAL IEQWNPVGLVGIITAFNFPVAVYGW NNAIAMICGNVCLWKGAPTTSLISV AVTKIIAKVLEDNKLPGAICSLTCG GADIGTAMAKDERVNLLSFTGSTQV GKQVGLMVQERFGRSLLELGGNNAI IAFEDADLSLVVPSALFAAVGTAGQ RCTTARRLFIHESIHDEVVNRLKKA YAQIRVGNPWDPNVLYGPLHTKQAV SMFLGAVEEAKKEGGTVVYGGKVMD RPGNYVEPTIVTGLGHDASIAHTET FAPILYVFKFKNEEEVFAWNNEVKQ GLSSSIFTKDLGRIFRWLGPKGSDC GIVNVNIPTSGAEIGGAFGGEKHTG GGRESGSDAWKQYMRRSTCTINYSK DLPLAQGIKFQ
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ALDH7A1 aldehyde dehydrogenase 7 family, member A1 [ Homo sapiens ]
• Official Symbol: ALDH7A1
• Synonyms: ALDH7A1; aldehyde dehydrogenase 7 family, member A1; ATQ1; alpha-aminoadipic semialdehyde dehydrogenase; 26g turgor protein homolog; alpha AASA dehydrogenase; alpha aminoadipic semialdehyde dehydrogenase; antiquitin 1; delta1 piperideine 6 carboxylate dehydrogenease; EPD; P6c dehydrogenase; PDE; antiquitin-1; alpha-AASA dehydrogenase; betaine aldehyde dehydrogenase; delta1-piperideine-6-carboxylate dehydrogenase; FLJ11738; FLJ92814
• Gene ID: 501
• mRNA Refseq: NM_001182
• Protein Refseq: NP_001173
• MIM: 107323
• UniProt ID: P49419