Recombinant Human ANXA1 Protein, His\Avi-tagged

• Cat.No.: ANXA1-213H
• Product Overview: Biotinylated Recombinant Human Annexin A1 is produced by E.coli. The target gene encoding A2- N346 is expressed with an Avi and 6His tag at the C terminus.

Specification

• Description: Annexin A1 is a member of the annexin family that can bind to cellular membranes in a calcium-dependent manner, promoting membrane fusion and endocytosis. Annexin A1 is found in the cytoplasm, on the cell surface, and in the extracellular fluid. Annexin A1 has anti-inflammatory activities and inhibits phospholipase A2 function. Annexin A1 is also involved in membrane aggregation, inflammation, phagocytosis, proliferation, apoptosis, and tumorigenesis and cancer development. It can exert both positive and negative effects on epithelial?mesenchymal transition and tumor metastasis.
• Source: E. coli
• Species: Human
• Tag: His\Avi
• Form: Lyophilized frum a 0.2 um filtered solution of 2umM Na2HPO4, 2umM NaH2PO4, pH7.4.
• Molecular Mass: Predicted Molecular Weight: 39.3kDa
  Apparent Molecular Weight: Biotinylated ANXA1 protein appeared at 38kDa in a reducing SDS-PAGE gel.
• AA Sequence: A2-N346
• Endotoxin: Less than 0.1 ng/ug (1 EU/ug).
• Purity: >95%
• Storage: Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks.
  Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days. Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months.
  Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
• Reconstitution: It is not recommended to reconstitute to a concentration less than 100μg/ml.
  Dissolve the lyophilized protein in distilled water.
  Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Quality Statement: Purity: greater than 95% as determined by reducing SDS-PAGE.
• Shipping: The product is shipped on dry ice pack.
  Upon receipt, store it immediately at the temperature listed below.

Gene Information

• Gene Name: ANXA1 annexin A1 [ Homo sapiens (human) ]
• Official Symbol: ANXA1
• Synonyms: Annexin A1; Annexin I; Annexin-1; Calpactin II; Calpactin-2; Chromobindin-9; Lipocortin I; Phospholipase A2 Inhibitory Protein; p35; ANX1; LPC1
• Gene ID: 301
• mRNA Refseq: NM_000700.3
• Protein Refseq: NP_000691.1
• MIM: 151690
• UniProt ID: P04083