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Recombinant Human ANXA13 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : ANXA13-6564H
Product Overview : ANXA13 MS Standard C13 and N15-labeled recombinant protein (NP_004297) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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Description : This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. The specific function of this gene has not yet been determined; however, it is associated with the plasma membrane of undifferentiated, proliferating endothelial cells and differentiated villus enterocytes. Alternatively spliced transcript variants encoding different isoforms have been identified.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 35.4 kDa
AA Sequence : MGNRHAKASSPQGFDVDRDAKKLNK ACKGMGTNEAAIIEILSGRTSDERQ QIKQKYKATYGKELEEVLKSELSGN FEKTALALLDHPSEYAARQLQKAMK GLGTDESVLIEVLCTRTNKEIIAIK EAYQRLFDRSLESDVKGDTSGNLKK ILVSLLQANRNEGDDVDKDLAGQDA KDLYDAGEGRWGTDELAFNEVLAKR SYKQLRATFQAYQILIGKDIEEAIE EETSGDLQKAYLTLVRCAQDCEDYF AERLYKSMKGAGTDEETLIRIIVTR AEVDLQGIKAKFQEKYQKSLSDMVR SDTSGDFRKLLVALLHTRTRPLEQK LISEEDLAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : ANXA13 annexin A13 [ Homo sapiens (human) ]
Official Symbol : ANXA13
Synonyms : ANXA13; annexin A13; ANX13; annexin-13; annexin XIII; intestine-specific annexin; annexin, intestine-specific; ISA; MGC150460;
Gene ID : 312
mRNA Refseq : NM_004306
Protein Refseq : NP_004297
MIM : 602573
UniProt ID : P27216

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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Are there any known mutations in the ANXA13 gene that are associated with disease? 02/02/2023

Currently, there are no known mutations in the ANXA13 gene that have been directly linked to any specific diseases. However, genetic variations in the ANXA13 gene may exist and could potentially contribute to disease susceptibility or affect ANXA13 function. Further studies are needed to explore the genetic variability of ANXA13 and its potential implications in various diseases.

What cellular compartments or organelles is ANXA13 localized to? 12/19/2019

ANXA13, like other annexin proteins, can be found in various cellular compartments or organelles. Annexin proteins have been detected on the plasma membrane, as well as in the cytoplasm, nucleus, mitochondria, endoplasmic reticulum, and lysosomes. The precise subcellular localization of ANXA13 may depend on the specific cell type and experimental conditions.

Are there any diseases associated with ANXA13 mutations or dysregulation? 08/02/2018

Mutations in the ANXA13 gene have been associated with certain diseases, such as amyloidosis. Amyloidosis is a disorder characterized by the abnormal accumulation of proteins in various tissues and organs, leading to organ dysfunction. However, research into the specific role of ANXA13 mutations in the development of amyloidosis is still ongoing.

Are there any diseases associated with ANXA13 mutations or dysregulation? 12/11/2017

Mutations in the ANXA13 gene have been associated with certain diseases, such as amyloidosis. Amyloidosis is a disorder characterized by the abnormal accumulation of proteins in various tissues and organs, leading to organ dysfunction. However, research into the specific role of ANXA13 mutations in the development of amyloidosis is still ongoing.

Is ANXA13 involved in cancer? 11/29/2016

ANXA13 has been implicated in certain cancers. For example, studies have suggested that ANXA13 may promote gastric cancer progression by influencing tumor cell growth and metastasis. However, the exact mechanisms and extent of ANXA13 involvement in cancer development and progression are not fully understood and require further investigation.

Is ANXA13 involved in any physiological processes? 04/21/2016

While the specific physiological processes involving ANXA13 are not well defined, annexins, in general, have been implicated in various cellular functions. Annexin proteins are known to be involved in membrane repair, membrane trafficking, regulation of ion channels, cell signaling, and apoptosis. It is possible that ANXA13 may have similar roles, but further research is needed to determine its specific functions.

In which tissues or organs is ANXA13 expressed? 03/05/2016

ANXA13 is known to be expressed in various tissues, including the brain, kidney, liver, lung, and pancreas, among others. Its expression pattern may vary depending on the cell type and developmental stage.

Customer Reviews (4)

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Reviews
03/16/2021

    Researchers can rely on the ANXA13 protein's specificity and sensitivity to obtain accurate and reliable results.

    01/12/2020

      the ANXA13 protein's versatility allows it to be effectively employed in various experimental designs, further enhancing its suitability for diverse research needs.

      01/23/2019

        The ANXA13 protein comes highly recommended for a variety of applications, particularly in ELISA and protein electron microscopy structure analysis.

        11/19/2016

          In protein electron microscopy structure analysis, the ANXA13 protein demonstrates outstanding performance.

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