| Description : |
The annexins are a family of calcium-dependent phospholipid-binding proteins. Members of the annexin family contain 4 internal repeat domains, each of which includes a type II calcium-binding site. The calcium-binding sites are required for annexins to aggregate and cooperatively bind anionic phospholipids and extracellular matrix proteins. This gene encodes a divergent member of the annexin protein family in which all four homologous type II calcium-binding sites in the conserved tetrad core contain amino acid substitutions that ablate their function. However, structural analysis suggests that the conserved putative ion channel formed by the tetrad core is intact. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
37.7 kDa |
| AA Sequence : |
MAPSLTQEILSHLGLASKTAAWGTL GTLRTFLNFSVDKDAQRLLRAITGQ GVDRSAIVDVLTNRSREQRQLISRN FQERTQQDLMKSLQAALSGNLERIV MALLQPTAQFDAQELRTALKASDSA VDVAIEILATRTPPQLQECLAVYKH NFQVEAVDDITSETSGILQDLLLAL AKGGRDSYSGIIDYNLAEQDVQALQ RAEGPSREETWVPVFTQRNPEHLIR VFDQYQRSTGQELEEAVQNRFHGDA QVALLGLASVIKNTPLYFADKLHQA LQETEPNYQVLIRILISRCETDLLS IRAEFRKKFGKSLYSSLQDAVKGDC QSALLALCRAEDMTRTRPLEQKLIS EEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
