Recombinant Human Annexin A9, His-tagged

• Cat.No.: ANXA9-5261H
• Product Overview: Recombinanthuman ANXA9 was expressed in E.coli with an N-terminal Histag.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: AnnexinA9 (ANXA9), otherwise known as ANXA31 and pemphaxin, is a calcium-dependentphospholipid-binding protein and member of the annexin family, expressed bystratified squamous skin epithelium, which may act as a low affinity receptorfor acetylcholine. ANXA9 is a target molecule for autoantibodies in patientswith the chronic autoimmune skin disease pemphigus vulgaris, characterised byepidermal blisters resulting from the loss of cell-cell adhesion.
• Form: Purified recombinantprotein-liquid.
• Application: ELISA; West Blotting
• Preparation: Purified recombinant6x His-tagged ANXA9 expressed in E.coli.
• Buffer Solution: 20mM, Tris-HCl 0.5MNaCl, 100mM Imidazole, 1mM Beta-mercaptoethanol, pH8.0.
• Molecular Weight: 29.3 kD (360 aminoacid residues with tag).
• Concentration: 0.5mg/ml
• Storage: Store at -70oC.Storage in frost-free freezers is not recommended. This product should bestored undiluted. Avoid repeated freezing and thawing as this may denaturethe antibody. Should this product contain a precipitate we recommendmicrocentrifugation before use.

Gene Information

• Gene Name: ANXA9 annexin A9 [ Homosapiens ]
• Official Symbol: ANXA9
• Synonyms: ANXA9;annexin A9; ANX31;annexin A9; annexin-9; pemphaxin; annexin 31; annexin-31; annexin XXXI;OTTHUMP00000033027
• Gene ID: 8416
• mRNA Refseq: NM_003568
• Protein Refseq: NP_003559
• MIM: 603319
• UniProt ID: O76027
• Chromosome Location: 1q21.2
• Function: acetylcholinereceptor activity; calcium ion binding; calcium-dependent phospholipidbinding; phosphatidylserine binding; phospholipid binding; proteinhomodimerization activity