| Description : |
The annexins are a family of calcium-dependent phospholipid-binding proteins. Members of the annexin family contain 4 internal repeat domains, each of which includes a type II calcium-binding site. The calcium-binding sites are required for annexins to aggregate and cooperatively bind anionic phospholipids and extracellular matrix proteins. This gene encodes a divergent member of the annexin protein family in which all four homologous type II calcium-binding sites in the conserved tetrad core contain amino acid substitutions that ablate their function. However, structural analysis suggests that the conserved putative ion channel formed by the tetrad core is intact. |
| Source : |
E. coli |
| Species : |
Human |
| Tag : |
His |
| Molecular Mass : |
29.3 kDa |
| Purity : |
>95% confirmed by 12% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-6xHis (WB). |
| Applications : |
ELISA, WB, Antibody Production, Protein array |
| Quality Control Test : |
12% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-6xHis (WB) serum and peptide fingerprinting by MALDI-TOF-TOF mass spectrometry. |
| Storage : |
Store working aliquots at 4 centigrade for up to one week.
For extended storage, conserve at −80 centigrade. |
| Expiry : |
12 months from the date of purchase, if it is properly stored. |
| Storage Buffer : |
20mM Tris-HCl, 0.5M NaCl, 100mM imidazole, 1mM 2-mercaptoethanol, pH:8.0 and contains not preservatives. |
| Shipping : |
Dry Ice |
