Recombinant Human ARMC4 protein, GST-tagged

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Recombinant Human ARMC4 protein, GST-tagged

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Cat.No. : ARMC4-828H
Product Overview : Human ARMC4 partial ORF ( NP_060546, 945 a.a. - 1044 a.a.) recombinant protein with GST-tag at N-terminal.
Description : The protein encoded by this gene contains ten Armadillo repeat motifs (ARMs) and one HEAT repeat, and is thought to be involved in ciliary and flagellar movement. This protein has been shown to localize to the ciliary axonemes and at the ciliary base of respiratory cells. Studies indicate that mutations in this gene cause partial outer dynein arm (ODA) defects in respiratory cilia. The cilia of cells with mutations in this gene displayed either reduced ciliary beat frequency and amplitude, or, complete immotility. Some individuals with primary ciliary dyskensia (PCD) have been shown to have mutations in this gene. PCD is characterized by chronic airway disease and left/right body asymmetry defects. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 36.74 kDa
AA Sequence : AISRCCMWGR NRVAFGEHKA VAPLVRYLKS NDTNVHRATA QALYQLSEDA DNCITMHENG AVKLLLDMVG SPDQDLQEAA AGCISNIRRL ALATEKARYT
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Figure :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : ARMC4 armadillo repeat containing 4 [ Homo sapiens ]
Official Symbol : ARMC4
Synonyms : ARMC4; armadillo repeat containing 4; armadillo repeat-containing protein 4; DKFZP434P1735; FLJ10376; FLJ10817; FLJ32798; RP11-691I13.1; DKFZp434P1735;
Gene ID : 55130
mRNA Refseq : NM_018076
Protein Refseq : NP_060546
UniProt ID : Q5T2S8
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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