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Recombinant Human ATG7 Protein, Myc/DDK-tagged, C13 and N15-labeled
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| Cat.No. : | ATG7-5180H |
| Product Overview : | ATG7 MS Standard C13 and N15-labeled recombinant protein (NP_006386) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
| Description : | This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 77.8 kDa |
| AA Sequence : | MAAATGDPGL SKLQFAPFSS ALDVGFWHEL TQKKLNEYRL DEAPKDIKGY YYNGDSAGLP ARLTLEFSAF DMSAPTPARC CPAIGTLYNT NTLESFKTAD KKLLLEQAAN EIWESIKSGT ALENPVLLNK FLLLTFADLK KYHFYYWFCY PALCLPESLP LIQGPVGLDQ RFSLKQIEAL ECAYDNLCQT EGVTALPYFL IKYDENMVLV SLLKHYSDFF QGQRTKITIG VYDPCNLAQY PGWPLRNFLV LAAHRWSSSF QSVEVVCFRD RTMQGARDVA HSIIFEVKLP EMAFSPDCPK AVGWEKNQKG GMGPRMVNLS ECMDPKRLAE SSVDLNLKLM CWRLVPTLDL DKVVSVKCLL LGAGTLGCNV ARTLMGWGVR HITFVDNAKI SYSNPVRQPL YEFEDCLGGG KPKALAAADR LQKIFPGVNA RGFNMSIPMP GHPVNFSSVT LEQARRDVEQ LEQLIESHDV VFLLMDTRES RWLPAVIAAS KRKLVINAAL GFDTFVVMRH GLKKPKQQGA GDLCPNHPVA SADLLGSSLF ANIPGYKLGC YFCNDVVAPG DSTRDRTLDQ QCTVSRPGLA VIAGALAVEL MVSVLQHPEG GYAIASSSDD RMNEPPTSLG LVPHQIRGFL SRFDNVLPVS LAFDKCTACS SKVLDQYERE GFNFLAKVFN SSHSFLEDLT GLTLLHQETQ AAEIWDMSDD ETITRTRPLE QKLISEEDLA ANDILDYKDD DDKV |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| SDS-PAGE : |
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| Gene Name : | ATG7 autophagy related 7 [ Homo sapiens (human) ] |
| Official Symbol : | ATG7 |
| Synonyms : | ATG7; ATG7 autophagy related 7 homolog (S. cerevisiae); APG7 autophagy 7 like (S. cerevisiae), APG7L; ubiquitin-like modifier-activating enzyme ATG7; DKFZp434N0735; GSA7; hAGP7; autophagy-related protein 7; ATG12-activating enzyme E1 ATG7; ubiquitin activating enzyme E1-like protein; ubiquitin-activating enzyme E1-like protein; APG7L; APG7-LIKE; |
| Gene ID : | 10533 |
| mRNA Refseq : | NM_006395 |
| Protein Refseq : | NP_006386 |
| MIM : | 608760 |
| UniProt ID : | O95352 |
◆ Recombinant Protein
| Atg7-1525M | Recombinant Mouse Atg7 Protein, His-tagged | +Inquiry |
| Atg7-1524M | Recombinant Mouse Atg7 Protein, His-tagged | +Inquiry |
| Atg7-1762M | Recombinant Mouse Atg7 Protein, Myc/DDK-tagged | +Inquiry |
| ATG7-1076H | Recombinant Human ATG7 Protein, His-tagged | +Inquiry |
| ATG7-127H | Recombinant Human full-length ATG7, GST-tagged | +Inquiry |
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◆ Lysates
| ATG7-8621HCL | Recombinant Human ATG7 293 Cell Lysate | +Inquiry |
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Atg12ATG3P1ATG5Atg7ATG16L1ATG4BATG4DATG3ATG4AATG4CATG10ATG8ATG16L2ATG2BATG9AATG9BATG9ATG13ATG14ATG2A
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