| Description : |
The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. |
| Source : |
Wheat Germ |
| Species : |
Human |
| Form : |
25 mM Tris-HCl of pH8.0 containing 2% glycerol. |
| Molecular Mass : |
60.2 kDa |
| AA Sequence : |
MPQLYIYIRLLGAYLFIISRVQGQN LDSMLHGTGMKSDSDQKKSENGVTL APEDTLPFLKCYCSGHCPDDAINNT CITNGHCFAIIEEDDQGETTLASGC MKYEGSDFQCKDSPKAQLRRTIECC RTNLCNQYLQPTLPPVVIGPFFDGS IRWLVLLISMAVCIIAMIIFSSCFC YKHYCKSISSRRRYNRDLEQDEAFI PVGESLKDLIDQSQSSGSGSGLPLL VQRTIAKQIQMVRQVGKGRYGEVWM GKWRGEKVAVKVFFTTEEASWFRET EIYQTVLMRHENILGFIAADIKGTG SWTQLYLITDYHENGSLYDFLKCAT LDTRALLKLAYSAACGLCHLHTEIY GTQGKPAIAHRDLKSKNILIKKNGS CCIADLGLAVKFNSDTNEVDVPLNT RVGTKRYMAPEVLDESLNKNHFQPY IMADIYSFGLIIWEMARRCITGGIV EEYQLPYYNMVPSDPSYEDMREVVC VKRLRPIVSNRWNSDECLRAVLKLM SECWAHNPASRLTALRIKKTLAKMV ESQDVKI |
| Usage : |
Heating may cause protein aggregation. Please do not heat this product before electrophoresis. |
| Notes : |
Best use within three months from the date of receipt of this protein. |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : |
25 mM Tris-HCl of pH8.0 containing 2% glycerol. |
