Recombinant Human Cancer/Testis Antigen 1B

• Cat.No.: CTAG1B-1512H
• Product Overview: Recombinant human full length NY-ESO-1 protein was expressed inE. coli.

Specification

• Cat. No.: CTAG1B-1512H
• Description: NY-ESO-1, a member of the CT (cancer/testis) family, is a tumor-specific shared antigen with distinctive immunogenicity. The molecular basis of T cell-mediated antitumor immunity has been elucidated by the identification of a number of tumor antigens recognized by CD8+ T cells. Among these antigens, NY-ESO-1 is of particular interest because both the cytotoxic T lymphocyte and antibody have been shown to react with this antigen. The NY-ESO- 1 has been detected in normal testis and in a range of human tumor types. NY-ESO-1 reactivity in testis is restricted to germ cells, particularly in the spermatogonia.
• Source: E. coli.
• Suggetsed Applications: ELISA, Inhibition Assays, Western Blotting. The optimal dilution for a specific application should be determined by the investigator.
• Supplied As: GST-NY-ESO-1 fusion protein was purified from E.coli and packaged at 100μg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA, 20% Glycerol.
• Characterization: On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 49kDa including GST.
• Storage And Stability: Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
• Tag: Non

Gene Information

• Gene Name: CTAG1B cancer/testis antigen 1B [ Homo sapiens ]
• Synonyms: CTAG1B; cancer/testis antigen 1B; CTAG; ESO1; CT6.1; CTAG1; LAGE-2; LAGE2B; NY-ESO-1; cancer antigen 3; New York esophageal squamous cell carcinoma 1; LAGE2A; Cancer/testis antigen 1; L antigen family member 2; Autoimmunogenic cancer/testis antigen NY-ESO-1; Cancer/testis antigen 6.1
• Gene ID: 1485
• mRNA Refseq: NM_001327
• Protein Refseq: NP_001318
• UniProt ID: P78358
• Chromosome Location: Xq28
• MIM: 300156

Reviews

02/22/2023

The Aldehyde Protein exhibits an exceptional level of quality that surpasses my experimental requirements.

03/02/2022

Its impeccable purity and consistency have consistently delivered accurate and robust results, enabling me to make significant strides in my research.

10/22/2016

One remarkable aspect of the CTAG1B Protein is the outstanding technical support provided by the manufacturer.

Q&As

How does CTAG1B contribute to the development of personalized cancer treatments?

CTAG1B expression profiling can help in tailoring personalized cancer treatments by identifying patients who may benefit from specific immunotherapeutic approaches.

How is the expression of CTAG1B in cancer cells significant for clinical applications?

The expression of CTAG1B in cancer cells is significant as it can serve as a potential biomarker for cancer diagnosis and prognosis.

In which cancers is CTAG1B protein commonly expressed?

CTAG1B expression is commonly observed in a variety of cancers, including melanoma, lung cancer, and bladder cancer.

Are there any specific diagnostic tests that utilize CTAG1B protein as a biomarker?

Yes, some diagnostic tests, such as immunohistochemistry (IHC), may use CTAG1B protein expression to aid in cancer diagnosis.

Can monitoring CTAG1B levels be useful during cancer treatment?

Yes, monitoring CTAG1B levels during cancer treatment can provide valuable information about the effectiveness of the therapy and potential relapse risks.