Recombinant Human Cancer/Testis Antigen 1B

Cat.No. : CTAG1B-1512H
Product Overview : Recombinant human full length NY-ESO-1 protein was expressed inE. coli.
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Cat. No. : CTAG1B-1512H
Description : NY-ESO-1, a member of the CT (cancer/testis) family, is a tumor-specific shared antigen with distinctive immunogenicity. The molecular basis of T cell-mediated antitumor immunity has been elucidated by the identification of a number of tumor antigens recognized by CD8+ T cells. Among these antigens, NY-ESO-1 is of particular interest because both the cytotoxic T lymphocyte and antibody have been shown to react with this antigen. The NY-ESO- 1 has been detected in normal testis and in a range of human tumor types. NY-ESO-1 reactivity in testis is restricted to germ cells, particularly in the spermatogonia.
Source : E. coli.
Suggetsed Applications : ELISA, Inhibition Assays, Western Blotting. The optimal dilution for a specific application should be determined by the investigator.
Supplied As : GST-NY-ESO-1 fusion protein was purified from E.coli and packaged at 100μg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA, 20% Glycerol.
Characterization : On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 49kDa including GST.
Storage And Stability : Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Gene Name : CTAG1B cancer/testis antigen 1B [ Homo sapiens ]
Synonyms : CTAG1B; cancer/testis antigen 1B; CTAG; ESO1; CT6.1; CTAG1; LAGE-2; LAGE2B; NY-ESO-1; cancer antigen 3; New York esophageal squamous cell carcinoma 1; LAGE2A; Cancer/testis antigen 1; L antigen family member 2; Autoimmunogenic cancer/testis antigen NY-ESO-1; Cancer/testis antigen 6.1
Gene ID : 1485
mRNA Refseq : NM_001327
Protein Refseq : NP_001318
UniProt ID : P78358
Chromosome Location : Xq28
MIM : 300156

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does CTAG1B contribute to the development of personalized cancer treatments? 11/02/2021

CTAG1B expression profiling can help in tailoring personalized cancer treatments by identifying patients who may benefit from specific immunotherapeutic approaches.

How is the expression of CTAG1B in cancer cells significant for clinical applications? 11/24/2020

The expression of CTAG1B in cancer cells is significant as it can serve as a potential biomarker for cancer diagnosis and prognosis.

In which cancers is CTAG1B protein commonly expressed? 10/14/2020

CTAG1B expression is commonly observed in a variety of cancers, including melanoma, lung cancer, and bladder cancer.

Are there any specific diagnostic tests that utilize CTAG1B protein as a biomarker? 11/26/2017

Yes, some diagnostic tests, such as immunohistochemistry (IHC), may use CTAG1B protein expression to aid in cancer diagnosis.

Can monitoring CTAG1B levels be useful during cancer treatment? 06/13/2017

Yes, monitoring CTAG1B levels during cancer treatment can provide valuable information about the effectiveness of the therapy and potential relapse risks.

Customer Reviews (3)

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Reviews
02/22/2023

    The Aldehyde Protein exhibits an exceptional level of quality that surpasses my experimental requirements.

    03/02/2022

      Its impeccable purity and consistency have consistently delivered accurate and robust results, enabling me to make significant strides in my research.

      10/22/2016

        One remarkable aspect of the CTAG1B Protein is the outstanding technical support provided by the manufacturer.

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