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Recombinant Human CAT Protein, GST-Tagged

Cat.No. : CAT-0443H
Product Overview : Human CAT full-length ORF (NP_001743.1, 1 a.a. - 527 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 86.2 kDa
AA Sequence : MADSRDPASDQMQHWKEQRAAQKAD VLTTGAGNPVGDKLNVITVGPRGPL LVQDVVFTDEMAHFDRERIPERVVH AKGAGAFGYFEVTHDITKYSKAKVF EHIGKKTPIAVRFSTVAGESGSADT VRDPRGFAVKFYTEDGNWDLVGNNT PIFFIRDPILFPSFIHSQKRNPQTH LKDPDMVWDFWSLRPESLHQVSFLF SDRGIPDGHRHMNGYGSHTFKLVNA NGEAVYCKFHYKTDQGIKNLSVEDA ARLSQEDPDYGIRDLFNAIATGKYP SWTFYIQVMTFNQAETFPFNPFDLT KVWPHKDYPLIPVGKLVLNRNPVNY FAEVEQIAFDPSNMPPGIEASPDKM LQGRLFAYPDTHRHRLGPNYLHIPV NCPYRARVANYQRDGPMCMQDNQGG APNYYPNSFGAPEQQPSALEHSIQY SGEVRRFNTANDDNVTQVRAFYVNV LNEEQRKRLCENIAGHLKDAQIFIQ KKAVKNFTEVHPDYGSHIQALLDKY NAEKPKNAIHTFVQSGSHLAAREKA NL
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : CAT catalase [ Homo sapiens ]
Official Symbol : CAT
Synonyms : CAT; catalase; MGC138422; MGC138424;
Gene ID : 847
mRNA Refseq : NM_001752
Protein Refseq : NP_001743
MIM : 115500
UniProt ID : P04040

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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