Recombinant Human CLCA1 Protein, His-tagged

• Cat.No.: CLCA1-08H
• Product Overview: Recombinant Human CLCA1 Protein, fused to His-tag, was expressed in E. coli.

Specification

• Description: This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Supplied as a 0.2 μm filtered solution in PBS (pH 7.4).
• Molecular Mass: ~73.6 KDa
• AA Sequence: NSLIQLNNNGYEGIVVAIDPNVPED ETLIQQIKDMVTQASLYLFEATGKR FYFKNVAILIPETWKTKADYVRPKL ETYKNADVLVAESTPPGNDEPYTEQ MGNCGEKGERIHLTPDFIAGKKLAE YGPQGRAFVHEWAHLRWGVFDEYNN DEKFYLSNGRIQAVRCSAGITGTNV VKKCQGGSCYTKRCTFNKVTGLYEK GCEFVLQSRQTEKASIMFAQHVDSI VEFCTEQNHNKEAPNKQNQKCNLRS TWEVIRDSEDFKKTTPMTTQPPNPT FSLLQIGQRIVCLVLDKSGSMATGN RLNRLNQAGQLFLLQTVELGSWVGM VTFDSAAHVQNELIQINSGSDRDTL AKRLPAAASGGTSICSGLRSAFTVI RKKYPTDGSEIVLLTDGEDNTISGC FNEVKQSGAIIHTVALGPSAAQELE ELSKMTGGLQTYASDQVQNNGLIDA FGALSSGNGAVSQRSIQLESKGLTL QNSQWMNGTVIVDSTVGKDTLFLIT WTMQPPQILLWDPSGQKQGGFVVDK NTKMAYLQIPGIAKVGTWKYSLQAS SQTLTLTVTSRASNATLPPITVTSK TNKDTSKFPSPLVVYANIRQGASPI LRASVTALIESVNGKTVTLELLDNG AGADATKDDGVYSRYFTTYDTNGRY SVKVRALGGVNAARRRVIPQQSG
• Purity: >85%
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 0.1 mg/ml
• Official Full Name: Chloride channel accessory 1

Gene Information

• Gene Name: CLCA1 chloride channel accessory 1 [ Homo sapiens (human) ]
• Official Symbol: CLCA1
• Synonyms: CACC; GOB5; CACC1; CLCRG1; CaCC-1; hCLCA1; hCaCC-1
• Gene ID: 1179
• mRNA Refseq: NM_001285
• Protein Refseq: NP_001276
• MIM: 603906
• UniProt ID: A8K7I4