Recombinant Human CXCL1, StrepII-tagged
|Product Overview :||Purified, full-length human recombinant GRO-alpha (CXCL1) protein (amino acids 35-107, 73 a.a.) with StrepII tag, produced in human cells. Predicted molecular weight: 11.3 kDa. (Accession NP_001502.1; UniProt P09341)|
- Gene Information
- Related Products
|Description :||GRO-alpha is a member of the CXC subfamily of chemokines. It is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity.|
|Source :||Human Cells|
|Form :||Lyophilized from sterile 0.2μm filtered solution in 0.3X PBS with 10% Trehalose (carrier-free)|
|Protein length :||35-107, 73 a.a.|
|AA Sequence :||MARAALSAAPSNPRLLRVALLLLLL VAAGRRAAGASVATELRCQCLQTLQ GIHPKNIQSVNVKSPGPHCAQTEVI ATLKNGRKACLNPASPIVKKIIEKM LNSDKSN|
|Endotoxin :||<0.1 eu per μg protein by lal|
|Purity :||>90% by SDS-PAGE|
|Storage :||12 months at -20°C as supplied; 1 month at 4°C after reconstitution. Avoid freeze/thaw cycles|
|Reconstitution :||Centrifuge the vial prior to opening. Reconstitute in PBS to a concentration of 0.1 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for up to 1 month.|
|Gene Name :||CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) [ Homo sapiens ]|
|Official Symbol :||CXCL1|
|Synonyms :||CXCL1; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha); fibroblast secretory protein , FSP, GRO1, GRO1 oncogene (melanoma growth stimulating activity, alpha) , MGSA; growth-regulated alpha protein; GROa; MGSA a; NAP 3; SCYB1; MGSA alpha; GRO-alpha(1-73); C-X-C motif chemokine 1; fibroblast secretory protein; neutrophil-activating protein 3; melanoma growth stimulatory activity alpha; GRO1 oncogene (melanoma growth-stimulating activity); GRO1 oncogene (melanoma growth stimulating activity, alpha); FSP; GRO1; MGSA; NAP-3; MGSA-a;|
|Gene ID :||2919|
|mRNA Refseq :||NM_001511|
|Protein Refseq :||NP_001502|
|UniProt ID :||P09341|
|Chromosome Location :||4q13.3|
|Pathway :||Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem;|
|Function :||chemokine activity; enzyme activator activity; growth factor activity; receptor binding;|
|◆ Recombinant Protein|
|CXCL1-272C||Active Recombinant Human CXCL1 Protein||+Inquiry|
|CXCL1-001H||Recombinant Human CXCL1 Protein, MBP-tagged||+Inquiry|
|Cxcl1-33M||Active Recombinant Mouse Cxcl1 Protein (Asn29-Lys96), Animal-free, Carrier-free||+Inquiry|
|Cxcl1-068M||Active Recombinant Mouse Cxcl1 Protein||+Inquiry|
|CXCL1-1345R||Recombinant Rat CXCL1 Protein, His (Fc)-Avi-tagged||+Inquiry|
|◆ Native Protein|
|CXCL1-27707TH||Native Human CXCL1||+Inquiry|
|CXCL1-425HCL||Recombinant Human CXCL1 cell lysate||+Inquiry|
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (7)Ask a question
Therapeutic strategies targeting CXCL1 aim to modulate its activity in diseases like cancer and chronic inflammation.
It mediates inflammation by promoting leukocyte migration and activation.
In cancer, CXCL1 can promote tumor growth, metastasis, and angiogenesis.
CXCL1 contributes to angiogenesis, supporting new blood vessel formation.
CXCL1 is a chemokine that attracts neutrophils to sites of infection or injury.
CXCL1 levels are elevated in conditions like cancer, inflammatory diseases, and infections.
CXCL1 expression is regulated by various stimuli, including cytokines and growth factors.
Customer Reviews (3)Write a review
Efficient delivery, great service. -
Product as described, perfect. -
Reliable for protein work. -
Ask a Question for All CXCL1 Products
Required fields are marked with *
My Review for All CXCL1 Products
Required fields are marked with *