Active Recombinant Human CXCL5 Protein (78 aa)
Cat.No. : | CXCL5-190C |
Product Overview : | Recombinant ENA-78/CXCL5 produced in 293 cells is a single polypeptide chain containing 78 amino acids. rhENA-78/CXCL5 has a molecular mass of 8.5 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Description : | Epithelial-derived neutrophil-activating peptide 78 (ENA-78) is a small cytokine belonging to the CXC chemokine family. It is produced following stimulation of cells with the inflammatory cytokines interleukin-1 or tumor necrosis factor-alpha. Expression of ENA-78 has also been observed in eosinophils, and can be inhibited with the type II interferon,IFN-γ. ENA-78 stimulates the chemotaxis of neutrophils possessing angiogenic properties. It plays a role in reducing sensitivity to sunburn pain in some subjects, and could be a potential target used to understand more about pain in other inflammatory conditions. ENA-78 is well known to have chemotactic and activating functions on neutrophils, mainly during acute inflammatory responses. It can signal through the CXCR2 receptor. |
Source : | HEK 293 |
Species : | Human |
Form : | Sterile Filtered White lyophilized (freeze-dried) powder. |
Bio-activity : | The EC50 value of human ENA-78/CXCL5 on Ca^2+ mobilization assay in CHO-K1/Gα15/hCXCR2 cells (human Gα15 and human CXCR2 stably expressed in CHO-K1 cells) is less than 200 ng/mL. |
Molecular Mass : | 8.5 kDa, observed by reducing SDS-PAGE. |
Protein Length : | 78 |
AA Sequence : | AGPAAAVLRELRCVCLQTTQGVHPK MISNLQVFAIGPQCSKVEVVASLKN GKEICLDPEAPFLKKVIQKILDGGN KEN |
Endotoxin : | < 0.2 EU/μg, determined by LAL method. |
Purity : | > 98% as analyzed by SDS-PAGE. |
Storage : | Lyophilized recombinant human ENA-78/CXCL5 remains stable up to 6 months at -80 centigrade from date of receipt. Upon reconstitution, human ENA-78/CXCL5 should be stable up to 1 week at 4 centigrade or up to 2 months at -20 centigrade. |
Storage Buffer : | Lyophilized after extensive dialysis against PBS. |
Reconstitution : | Reconstituted in ddH2O or PBS at 100 μg/mL. |
Gene Name : | CXCL5 chemokine (C-X-C motif) ligand 5 [ Homo sapiens ] |
Official Symbol : | CXCL5 |
Synonyms : | CXCL5; chemokine (C-X-C motif) ligand 5; SCYB5, small inducible cytokine subfamily B (Cys X Cys), member 5 (epithelial derived neutrophil activating peptide 78); C-X-C motif chemokine 5; ENA 78; ENA-78(1-78); small inducible cytokine B5; small-inducible cytokine B5; neutrophil-activating protein 78; neutrophil-activating peptide ENA-78; epithelial-derived neutrophil activating protein 78; epithelial-derived neutrophil-activating peptide 78; epithelial-derived neutrophil-activating protein 78; small inducible cytokine subfamily B (Cys-X-Cys), member 5 (epithelial-derived neutrophil-activating peptide 78); SCYB5; ENA-78; |
Gene ID : | 6374 |
mRNA Refseq : | NM_002994 |
Protein Refseq : | NP_002985 |
MIM : | 600324 |
UniProt ID : | P42830 |
Products Types
◆ Recombinant Protein | ||
CXCL5-131C | Active Recombinant Human CXCL5 Protein (74 aa) | +Inquiry |
Cxcl5-79M | Active Recombinant Mouse Cxcl5 Protein (Val1-Ala118), N-His tagged, Animal-free, Carrier-free | +Inquiry |
CXCL5-01C | Recombinant Cynomolgus CXCL5 Protein | +Inquiry |
Cxcl5-227C | Active Recombinant Rat Cxcl5 Protein (88 aa) | +Inquiry |
Cxcl5-2398M | Active Recombinant Mouse Cxcl5 Protein | +Inquiry |
◆ Lysates | ||
CXCL5-7167HCL | Recombinant Human CXCL5 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket