Recombinant Human DDX20 Protein, GST-tagged

• Cat.No.: DDX20-2471H
• Product Overview: Human DDX20 full-length ORF ( AAH34953, 1 a.a. - 824 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. This protein interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 116.38 kDa
• AA Sequence: MAAAFEASGALAAVATAMPAEHVAV QVPAPEPTPGPVRILRTAQDLSSPR TRTGDVLLAEPADFESLLLSRPVLE GLRAAGFERPSPVQLKAIPLGRCGL DLIVQAKSGTGKTCVFSTIALDSLV LENLSTQILILAPTREIAVQIHSVI TAIGIKMEGLECHVFIGGTPLSQDK TRLKKCHIAVGSPGRIKQLIELDYL NPGSIRLFILDEADKLLEEGSFQEQ INWIYSSLPASKQMLAVSATYPEFL ANALTKYMRDPTFVRLNSSDPSLIG LKQYYKVVNSYPLAHKVFEEKTQHL QELFSRIPFNQALVFSNLHSRAQHL ADILSSKGFPAECISGNMNQNQRLD AMAKLKHFHCRVLISTDLTSRGIDA EKVNLVVNLDVPLDWETYMHRIGRA GRFGTLGLTVTYCCRGEEGNMMMRI AQKCNINLLPLPDPIPSGLMEECVD WDVEVKAAVHTYGIASVPNQPLKKQ IQKIERTLQIQKAHGDHMASSRNNS VSGLSVKSKNNTKQKLPVKSHSECG IIEKATSPKELGCDRQSEEQMKNSV QTPVENSTNSQHQVKEALPVSLPQI PCLSSFKIHQPYTLTFAELVEDYEH YIKEGLEKPVEIIRHYTGPGDQTVN PQNGFVRNKVTEQRVPVLASSSQSG DSESDSDSYSSRTSSQSKGNKSYLE GSSDNQLKDSESTPVDDRISLEQPP NGSDTPNPEKYQESPGIQMKTRLKE GASQRAKQSRRNLPRRSSFRLQTEA QEDDWYDCHREIRLSFSDTYQDYEE YWRAYYRAWQEYYAAASHSYYWNAQ RHPSWMAAYHMNTIYLQEMMHSNQ
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 [ Homo sapiens ]
• Official Symbol: DDX20
• Synonyms: DDX20; DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 20, 103kD; probable ATP-dependent RNA helicase DDX20; DP103; GEMIN3; gemin-3; DEAD box protein 20; component of gems 3; DEAD-box protein DP103; DEAD box protein DP 103; SMN-interacting protein; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 20, 103kD; DKFZp434H052
• Gene ID: 11218
• mRNA Refseq: NM_007204
• Protein Refseq: NP_009135
• MIM: 606168
• UniProt ID: Q9UHI6