| Cat.No. : |
DLK1-2683H |
| Product Overview : |
Human DLK1 full-length ORF ( AAH07741.1, 25 a.a. - 383 a.a.) recombinant protein with GST-tag at N-terminal. |
| Description : |
This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal. [provided by RefSeq, Nov 2015] |
| Source : |
Wheat Germ |
| Species : |
Human |
| Tag : |
GST |
| Molecular Mass : |
65.23 kDa |
| AA Sequence : |
ECFPACNPQN GFCEDDNVCR CQPGWQGPLC DQCVTSPGCL HGLCGEPGQC ICTDGWDGEL CDRDVRACSS APCANNGTCV SLDDGLYECS RAPGYSGKDC QKKDGPCVIN GSPCQHGGTC VDDEGRASHA SCLCPPGFSG NFCEIVANSC TPNPCENDGV CTDIGGDFRC RCPAGFIDKT CSRPVTNCAS SPCQNGGTCL QHTQVSYECL CKPEFTGLTC VKKRALSPQQ VTRLPNGYGL AYRLTPGVHE LPVQQPEHRI LKVSMKELNK KTPLLTEGQA ICFTILGVLT SLVVLGTVGI VFLNKCETWV SNLRYNHMLR KKKNLLLQYN SGEDLAVNII FPEKIDMTTF SKEAGDEEI |
| Applications : |
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array |
| Notes : |
Best use within three months from the date of receipt of this protein. |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Quality Control Testing : |
12.5% SDS-PAGE Stained with Coomassie Blue.
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