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Recombinant Human DOK5 Protein, GST-tagged

Cat.No. : DOK5-2813H
Product Overview : Human DOK5 full-length ORF ( NP_060901.2, 1 a.a. - 306 a.a.) recombinant protein with GST-tag at N-terminal.
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  • Gene Information
  • Related Products
Description : The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. Unlike other DOK family proteins, this protein does not interact with RASGAP. This protein is up-regulated in patients with systemic sclerosis and is associated with fibrosis induced by insulin-like growth factor binding protein 5. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 61.9 kDa
AA Sequence : MASNFNDIVKQGYVRIRSRRLGIYQ RCWLVFKKASSKGPKRLEKFSDERA AYFRCYHKVTELNNVKNVARLPKST KKHAIGIYFNDDTSKTFACESDLEA DEWCKVLQMECVGTRINDISLGEPD LLATGVEREQSERFNVYLMPSPNLD VHGECALQITYEYICLWDVQNPRVK LISWPLSALRRYGRDTTWFTFEAGR MCETGEGLFIFQTRDGEAIYQKVHS AALAIAEQHERLLQSVKNSMLQMKM SERAASLSTMVPLPRSAYWQHITRQ HSTGQLYRLQDVSSPLKLHRTETFP AYRSEH
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : DOK5 docking protein 5 [ Homo sapiens ]
Official Symbol : DOK5
Synonyms : DOK5; docking protein 5; C20orf180, chromosome 20 open reading frame 180; dJ805C22.1; IRS6; IRS-6; insulin receptor substrate 6; downstream of tyrosine kinase 5; C20orf180; MGC16926;
Gene ID : 55816
mRNA Refseq : NM_018431
Protein Refseq : NP_060901
MIM : 608334
UniProt ID : Q9P104

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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