Recombinant Human DUSP13 Protein, GST-tagged

• Cat.No.: DUSP13-2927H
• Product Overview: Human DUSP13 full-length ORF ( AAH09778, 1 a.a. - 198 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Members of the protein-tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and differentiation. This superfamily is separated into two families based on the substrate that is dephosphorylated. One family, the dual specificity phosphatases (DSPs) acts on both phosphotyrosine and phosphoserine/threonine residues. This gene encodes different but related DSP proteins through the use of non-overlapping open reading frames, alternate splicing, and presumed different transcription promoters. Expression of the distinct proteins from this gene has been found to be tissue specific and the proteins may be involved in postnatal development of specific tissues. A protein encoded by the upstream ORF was found in skeletal muscle, whereas the encoded protein from the downstream ORF was found only in testis. In mouse, a similar pattern of expression was found. Multiple alternatively spliced transcript variants were described, but the full-length sequence of only some were determined. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 47.52 kDa
• AA Sequence: MDSLQKQDLRRPKIHGAVQASPYQP PTLASLQRLLWVRQAATLNHIDEVW PSLFLGDAYAARDKSKLIQLGITHV VNAAAGKFQVDTGAKFYRGMSLEYY GIEADDNPFFDLSVYFLPVARYIRA ALSVPQGRVLVHCAMGVSRSATLVL AFLMIYENMTLVEAIQTVQAHRNIC PNSGFLRQLQVLDNRLGRETGRF
• Applications: Phosphatase Assay (Cdc25)
  Phosphatase Assay (PTP)
  Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DUSP13 dual specificity phosphatase 13 [ Homo sapiens ]
• Official Symbol: DUSP13
• Synonyms: DUSP13; dual specificity phosphatase 13; dual specificity protein phosphatase 13; BEDP; DUSP13A; DUSP13B; FLJ32450; TMDP; muscle-restricted DSP; branching-enzyme interacting DSP; dual specificity phosphatase SKRP4; testis- and skeletal-muscle-specific DSP; branching-enzyme interacting dual-specificity protein phosphatase; MDSP; SKRP4
• Gene ID: 51207
• mRNA Refseq: NM_001007271
• Protein Refseq: NP_001007272
• MIM: 613191
• UniProt ID: Q6B8I1