Recombinant Human ECE1 Protein, GST-tagged

• Cat.No.: ECE1-3027H
• Product Overview: Human ECE1 full-length ORF ( NP_001388.1, 1 a.a. - 770 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is involved in proteolytic processing of endothelin precursors to biologically active peptides. Mutations in this gene are associated with Hirschsprung disease, cardiac defects and autonomic dysfunction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Sep 2009]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 113.6 kDa
• AA Sequence: MRGVWPPPVSALLSALGMSTYKRAT LDEEDLVDSLSEGDAYPNGLQVNFH SPRSGQRCWAARTQVEKRLVVLVVL LAAGLVACLAALGIQYQTRSPSVCL SEACVSVTSSILSSMDPTVDPCHDF FSYACGGWIKANPVPDGHSRWGTFS NLWEHNQAIIKHLLENSTASVSEAE RKAQVYYRACMNETRIEELRAKPLM ELIERLGGWNITGPWAKDNFQDTLQ VVTAHYRTSPFFSVYVSADSKNSNS NVIQVDQSGLGLPSRDYYLNKTENE KVLTGYLNYMVQLGKLLGGGDEEAI RPQMQQILDFETALANITIPQEKRR DEELIYHKVTAAELQTLAPAINWLP FLNTIFYPVEINESEPIVVYDKEYL EQISTLINTTDRCLLNNYMIWNLVR KTSSFLDQRFQDADEKFMEVMYGTK KTCLPRWKFCVSDTENNLGFALGPM FVKATFAEDSKSIATEIILEIKKAF EESLSTLKWMDEETRKSAKEKADAI YNMIGYPNFIMDPKELDKVFNDYTA VPDLYFENAMRFFNFSWRVTADQLR KAPNRDQWSMTPPMVNAYYSPTKNE IVFPAGILQAPFYTRSSPKALNFGG IGVVVGHELTHAFDDQGREYDKDGN LRPWWKNSSVEAFKRQTECMVEQYS NYSVNGEPVNGRHTLGENIADNGGL KAAYRAYQNWVKKNGAEHSLPTLGL TNNQLFFLGFAQVWCSVRTPESSHE GLITDPHSPSRFRVIGSLSNSKEFS EHFRCPPGSPMNPPHKCEVW
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ECE1 endothelin converting enzyme 1 [ Homo sapiens ]
• Official Symbol: ECE1
• Synonyms: ECE1; endothelin converting enzyme 1; ECE; endothelin-converting enzyme 1; ECE-1
• Gene ID: 1889
• mRNA Refseq: NM_001113347
• Protein Refseq: NP_001106818
• MIM: 600423
• UniProt ID: P42892