Recombinant Human EIF4E Protein (M1-V217), His tagged
Cat.No. : | EIF4E-1002H |
Product Overview : | Recombinant Human 6His-TEV-EIF4E(M1-V217 end) Protein was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. In addition to its role in translation initiation, also acts as a regulator of translation and stability in the cytoplasm. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression: in the complex, EIF4E mediates the binding to the mRNA cap. Component of a multiprotein complex that sequesters and represses translation of proneurogenic factors during neurogenesis. In P-bodies, component of a complex that mediates the storage of translationally inactive mRNAs in the cytoplasm and prevents their degradation. May play an important role in spermatogenesis through translational regulation of stage-specific mRNAs during germ cell development. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid |
Protein Length : | M1-V217 |
Endotoxin : | < 0.01 EU per μg of the protein |
Purity : | 90% |
Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol |
Shipping : | It is shipped out with blue ice. |
Gene Name : | EIF4E eukaryotic translation initiation factor 4E [ Homo sapiens (human) ] |
Official Symbol : | EIF4E |
Synonyms : | EIF4E; eukaryotic translation initiation factor 4E; EIF4EL1, EIF4F; EIF4E1; eIF-4E; eIF-4F 25 kDa subunit; mRNA cap-binding protein; eukaryotic translation initiation factor 4E-like 1; CBP; EIF4F; EIF4EL1; MGC111573; |
Gene ID : | 1977 |
mRNA Refseq : | NM_001130678 |
Protein Refseq : | NP_001124150 |
MIM : | 133440 |
UniProt ID : | P06730 |
Products Types
◆ Recombinant Protein | ||
EIF4E-39H | Recombinant Human EIF4E Protein (1-217), N-His tagged | +Inquiry |
Eif4e-811M | Recombinant Mouse Eif4e Protein, MYC/DDK-tagged | +Inquiry |
EIF4E-3198H | Recombinant Human EIF4E Protein, GST-tagged | +Inquiry |
EIF4E-40H | Recombinant Human EIF4E Protein Complexed With EIF4G (1-217), N-His tagged | +Inquiry |
EIF4E-1723R | Recombinant Rat EIF4E Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
EIF4E-6651HCL | Recombinant Human EIF4E 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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