Description : |
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
His |
Form : |
Lyophilized |
Molecular Mass : |
57.8 kDa |
Protein Length : |
987 |
AA Sequence : |
MELRVLLCWASLAAALEETLLNTKL ETADLKWVTFPQVDGQWEELSGLDE EQHSVRTYEVCDVQRAPGQAHWLRT GWVPRRGAVHVYATLRFTMLECLSL PRAGRSCKETFTVFYYESDADTATA LTPAWMENPYIKVDTVAAEHLTRKR PGAEATGKVNVKTLRLGPLSKAGFY LAFQDQGACMALLSLHLFYKKCAQL TVNLTRFPETVPRELVVPVAGSCVV DAVPAPGPSPSLYCREDGQWAEQPV TGCSCAPGFEAAEGNTKCRACAQGT FKPLSGEGSCQPCPANSHSNTIGSA VCQCRVGYFRARTDPRGAPCTTPPS APRSVVSRLNGSSLHLEWSAPLESG GREDLTYALRCRECRPGGSCAPCGG DLTFDPGPRDLVEPWVVVRGLRPDF TYTFEVTALNGVSSLATGPVPFEPV NVTTDREVPPAVSDIRVTRSSPSSL SLAWAVPRAPSGAVLDYEVKYHEKG AEGPSSVRFLKTSENRAELRGLKRG ASYLVQVRARSEAGYGPFGQEHHSQ TQLDESEGWREQLALIAGTAVVGVV LVLVVIVVAVLCLRKQSNGREAEYS DKHGQYLIGHGTKVYIDPFTYEDPN EAVREFAKEIDVSYVKIEEVIGAGE FGEVCRGRLKAPGKKESCVAIKTLK GGYTERQRREFLSEASIMGQFEHPN IIRLEGVVTNSMPVMILTEFMENGA LDSFLRLNDGQFTVIQLVGMLRGIA SGMRYLAEMSYVHRDLAARNILVNS NLVCKVSDFGLSRFLEENSSDPTYT SSLGGKIPIRWTAPEAIAFRKFTSA SDAWSYGIVMWEVMSFGERPYWDMS NQDVINAIEQDYRLPPPPDCPTSLH QLMLDCWQKDRNARPRFPQVVSALD KMIRNPASLKIVARENGGASHPLLD QRQPHYSAFGSVGEWLRAIKMGRYE ESFAAAGFGSFELVSQISAEDLLRI GVTLAGHQKKILASVQHMKSQAKPG TPGGTGGPAPQY |
Purity : |
> 98% |
Applications : |
WB; ELISA; FACS; FC |
Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
Storage : |
At -20 centigrade. |
Concentration : |
1 mg/mL |
Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |